Document Detail

Previous pregnancy outcomes and subsequent risk of preterm rupture of amniotic sac membranes.
MedLine Citation:
PMID:  8334088     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To test the hypothesis that previous unfavourable pregnancy outcomes increase the risk for premature birth, with (PP) or without (PTB) premature rupture of the amniotic sac (PROM) at the index pregnancy and that multiple undesirable outcomes increase risk. DESIGN: Case control study. SETTING: Two university hospitals. SUBJECTS: Four hundred sixty-three women aged 15 to 45 years who were delivered preterm PROM, full term PROM and preterm without PROM matched with 463 women who delivered full term. All women included in the study had at least one previous pregnancy. OUTCOME MEASURES: Odds ratio of previous adverse pregnancy outcome among index cases. RESULTS: Compared with controls, PP cases had odds ratios of 95 for previous preterm birth, 186 for abortion and prematurity and 158 for fetal loss, abortion/prematurity after controlling for confounding variables. Compared with controls, PTB cases had an odds ratio of 96.5 for previous preterm delivery, 84 for abortion and prematurity, and 320 for fetal loss/abortion and prematurity after controlling for confounding variables. CONCLUSIONS: Previous preterm delivery, abortion and prematurity and fetal loss/abortion and prematurity all increase risk for subsequent preterm birth with or without PROM.
E E Ekwo; C A Gosselink; A Moawad
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  British journal of obstetrics and gynaecology     Volume:  100     ISSN:  0306-5456     ISO Abbreviation:  Br J Obstet Gynaecol     Publication Date:  1993 Jun 
Date Detail:
Created Date:  1993-08-23     Completed Date:  1993-08-23     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7503752     Medline TA:  Br J Obstet Gynaecol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  536-41     Citation Subset:  AIM; IM    
University of Chicago Pritzker School of Medicine.
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MeSH Terms
Abortion, Spontaneous
Case-Control Studies
Fetal Membranes, Premature Rupture / etiology*
Infant, Newborn
Infant, Premature
Infant, Small for Gestational Age
Obstetric Labor, Premature / etiology*
Pregnancy Outcome*
Risk Factors
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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