Document Detail

Previous enteric adenovirus infection does not protect against subsequent symptomatic infection: longitudinal follow-up of eight infants.
MedLine Citation:
PMID:  8867613     Owner:  NLM     Status:  MEDLINE    
Eight infants followed longitudinally were found to have enteric adenovirus (EAdv) infections: in 5 infants with diarrhea and in 3 with no accompanying diarrhea. Sequential stool samples prior to EAdv infections were tested for adenovirus antigen, anti-adenoviral IgA and neutralizing antibodies to serotypes 40, 41 and 2 in order to ascertain whether protection from symptoms was due to prior infection. No difference was found in the number of adenoviral infections among infants prior to their EAdv infections with or without accompanying diarrhea. However, in 3 of the 5 infants in whom EAdv infection was accompanied by diarrhea and 2 of 3 control infants, previous EAdv infections had occurred as detected by serotype-specific antibody rises.
L E Unicomb; K Jarecki-Khan; A Hall; G Podder
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Microbiology and immunology     Volume:  40     ISSN:  0385-5600     ISO Abbreviation:  Microbiol. Immunol.     Publication Date:  1996  
Date Detail:
Created Date:  1996-12-05     Completed Date:  1996-12-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7703966     Medline TA:  Microbiol Immunol     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  161-8     Citation Subset:  IM    
International Centre for Diarrhoeal Disease Research, Bangladesh.
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MeSH Terms
Adenoviridae Infections / immunology*
Adenoviruses, Human / immunology*,  metabolism
Antibodies, Viral / immunology
Cell Line, Transformed
Child, Preschool
Feces / virology
Follow-Up Studies
Giardia lamblia
Hela Cells
Longitudinal Studies
Reg. No./Substance:
0/Antibodies, Viral

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