Document Detail


Preventive effect of whey hydrolysate formulas for mothers and infants against allergy development in infants for the first 2 years.
MedLine Citation:
PMID:  9268927     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We studied the preventive effect against allergies in infants who and whose mothers consumed hypoallergenic formulas until 6 months after birth. Mother and infant pairs were divided into three groups, and the infants were monitored for the development of allergies for the first 2 years. In the MD group (n = 102; n = number of infants), the mothers were given a hypoallergenic formula for mothers (MOM HA), which contained hydrolyzed whey protein as the only protein source, as a substitution for cow's milk during late pregnancy and lactation. In the CD group (n = 127), the mothers were given cow's milk during the corresponding period. All infants in the MD and CD groups were exclusively breast-fed or mixed-fed with breast milk and hypoallergenic infant formula (NAN HA), which contains the same hydrolyzed protein as MOM HA. In the AF group (n = 54), the mothers consumed MOM HA and their infants were mixed-fed with breast milk and a cow's milk-based adopted infant formula during the corresponding period. In the MD group, no infants were positive to cow's milk-specific immunoglobulin E (RAST) at 4 months of age, in contrast to 6% and 3% of infants in the CD and AF groups, respectively. The infants in the MD group showed low incidence of various allergies, especially of eczema, as compared to the CD and AF groups. These results suggest that consumption of cow's milk by mothers and cow's milk-based formula feeding to infants elevate the risk of allergies in infants, and that consumption of hypoallergenic formula for pregnant and lactating women and for infants could be helpful in preventing allergy development in infants.
Authors:
Y Fukushima; K Iwamoto; A Takeuchi-Nakashima; N Akamatsu; N Fujino-Numata; M Yoshikoshi; T Onda; M Kitagawa
Related Documents :
7196907 - Bovine salmonellosis attributed to salmonella anatum-contaminated haylage and dietary s...
17636737 - Withdrawn: cow's milk protein avoidance and development of childhood wheeze in children...
15564777 - Japanese cedar-pollen-specific il-5 production in infants with atopic dermatitis.
21099447 - Th1 and th2 chemokines, vaccine-induced immunity, and allergic disease in infants after...
20734557 - Reexamining the dominance of birth cohort effects on mortality.
19127877 - Life and death in freudian metapsychology: a reappraisal of the second instinctual dual...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of nutritional science and vitaminology     Volume:  43     ISSN:  0301-4800     ISO Abbreviation:  J. Nutr. Sci. Vitaminol.     Publication Date:  1997 Jun 
Date Detail:
Created Date:  1997-10-01     Completed Date:  1997-10-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0402640     Medline TA:  J Nutr Sci Vitaminol (Tokyo)     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  397-411     Citation Subset:  IM    
Affiliation:
Scientific Liaison Office, Nestlé Japan Ltd., Tokyo, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Dairy Products*
Female
Humans
Hypersensitivity / prevention & control*
Immunoglobulin E / blood
Infant
Infant Food*
Infant, Newborn
Odds Ratio
Pregnancy
Risk Factors
Chemical
Reg. No./Substance:
37341-29-0/Immunoglobulin E

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Role of ornithine transport into mitochondria in urea synthesis of rats treated in thyroid hormone.
Next Document:  Maximal stationary metabolic rate in free-moving rats.