| Prevention of ventricular fibrillation with magnesium sulfate. | |
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MedLine Citation:
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PMID: 3220116 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Mongrel dogs with healed myocardial infarctions were given a 2 min coronary occlusion during an exercise test. The exercise plus ischemia test induced ventricular fibrillation in nine animals. One week later, the test was repeated after pretreatment with magnesium sulfate (100 mg/kg i.v.). Magnesium prevented ventricular fibrillation in seven of the nine animals without adverse side effects. Thus, magnesium may be useful in the management of ventricular fibrillation during ischemia. |
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Authors:
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G E Billman; R S Hoskins |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: European journal of pharmacology Volume: 158 ISSN: 0014-2999 ISO Abbreviation: Eur. J. Pharmacol. Publication Date: 1988 Dec |
Date Detail:
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Created Date: 1989-03-17 Completed Date: 1989-03-17 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 1254354 Medline TA: Eur J Pharmacol Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 167-71 Citation Subset: IM |
Affiliation:
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Department of Physiology, Ohio State University, Columbus 43210-1239. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Coronary Disease / complications, physiopathology Dogs Hemodynamics / drug effects Magnesium Sulfate / pharmacology* Myocardial Infarction / complications, physiopathology Physical Exertion Ventricular Fibrillation / etiology, prevention & control* |
| Grant Support | |
ID/Acronym/Agency:
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HL 36336/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
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7487-88-9/Magnesium Sulfate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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