Document Detail

Prevention of transfusion-associated HIV transmission in Kinshasa, Zaire: HIV screening is not enough.
MedLine Citation:
PMID:  2386619     Owner:  NLM     Status:  MEDLINE    
The purpose of this study was to develop a strategy to reduce transfusion-related HIV transmission which went beyond the limits of routine HIV screening of blood donors. Current blood transfusion practices were assessed in 1044 patients for whom staff physicians had requested a transfusion between 5 September and 19 October, 1988. Children under 5 years of age with malaria, and pregnant women with acute anaemia requiring blood transfusion were the two highest risk groups. Many of the transfusions were given without an obvious medical indication; 22.7% (214 out of 955) of the recipients were transfused without prior laboratory tests [haemoglobin (Hb) or haematocrit (Hct)], 7.2% with Hb greater than 6g/100ml or Hct greater than 25% and 16.6% without clinical signs of severe anaemia (pulse less than 100/min without shortness of breath). The data of this study were used to organize a workshop for all the physicians responsible for blood transfusions in Kinshasa and two nearby health zones. A consensus statement on the indications for blood transfusion was developed. Subsequently, transfusion centres adopted this consensus statement instead of previous guidelines.
H Jäger; B N'Galy; J Perriens; K Nseka; F Davachi; C M Kabeya; G Rauhaus; G Peyerl; R W Ryder; T Rehle
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  AIDS (London, England)     Volume:  4     ISSN:  0269-9370     ISO Abbreviation:  AIDS     Publication Date:  1990 Jun 
Date Detail:
Created Date:  1990-09-25     Completed Date:  1990-09-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8710219     Medline TA:  AIDS     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  571-4     Citation Subset:  IM; X    
Deutsche Gesellschaft für Technische Zusammenarbeit, (GTZ) GmbH, Eschborn, FRG.
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MeSH Terms
Anemia / complications,  prevention & control
Blood Donors
Blood Transfusion* / adverse effects
Child, Preschool
Democratic Republic of the Congo
HIV Infections / complications,  prevention & control,  transmission*
Health Planning Guidelines
Infant, Newborn
Malaria / complications,  prevention & control,  transmission
Pregnancy Complications
Risk Factors

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