| Prevention of tourniquet pain by spinal isobaric bupivacaine with clonidine. | |
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MedLine Citation:
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PMID: 2765348 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In order to assess the effect of spinal clonidine on tourniquet pain, 30 patients scheduled to undergo orthopaedic surgery under spinal anaesthesia were allocated randomly to two groups. Patients in group I (n = 15) received 0.5% isobaric bupivacaine 15 mg plus isotonic saline 1 ml. Patients in group II (n = 15) received 0.5% bupivacaine 15 mg plus clonidine 1 ml (150 micrograms). Sensory block was evaluated by pinprick and motor block with Bromage's scale. The presence of clonidine significantly prolonged the duration of sensory and motor block. Three patients in group I, but none in group II, experienced tourniquet pain. Hypotension and bradycardia were not worsened by spinal clonidine. The use of clonidine may be a useful technique to augment bupivacaine spinal block. |
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Authors:
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F Bonnet; A Diallo; M Saada; M Belon; M Guilbaud; O Boico |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: British journal of anaesthesia Volume: 63 ISSN: 0007-0912 ISO Abbreviation: Br J Anaesth Publication Date: 1989 Jul |
Date Detail:
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Created Date: 1989-09-28 Completed Date: 1989-09-28 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372541 Medline TA: Br J Anaesth Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 93-6 Citation Subset: IM |
Affiliation:
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Département d'Anesthésie Réanimation No. II, Hôpital Henri Mondor, Creteil, France. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Anesthesia, Spinal* Bupivacaine* / administration & dosage Clonidine* / administration & dosage Drug Evaluation Female Humans Male Pain / prevention & control* Prospective Studies Random Allocation Sensation / drug effects Specific Gravity Time Factors Tourniquets / adverse effects* |
| Chemical | |
Reg. No./Substance:
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2180-92-9/Bupivacaine; 4205-90-7/Clonidine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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