Document Detail

Prevention and reversal of lung collapse during the intra-operative period.
MedLine Citation:
PMID:  20608556     Owner:  NLM     Status:  MEDLINE    
General anaesthesia induces ventilation/perfusion mismatch by lung collapse. Such lung collapse predisposes patients to preoperative complications since it can persist for several hours or days after surgery. Atelectasis can be partially prevented by using continuous positive airway pressure (CPAP) and/or by lowering FiO2 during anaesthesia induction. However, these manoeuvres are dangerous for patients presenting with challenging airway or ventilator conditions. Lung recruitment manoeuvres (RMs) are ventilatory strategies that aim to restore the aeration of normal lungs. They consist of a brief and controlled increment in airway pressure to open up collapsed areas of the lungs and sufficient positive end-expiratory pressure (PEEP) to keep them open afterward. The application of RMs during anaesthesia normalises lung function along the intraoperative period. There is physiological evidence that patients of all ages and any kind of surgery benefit from such an active intervention. The effect of RMs on patient outcome in the postoperative period is, however, not yet known.
Gerardo Tusman; Stephan H Böhm
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Best practice & research. Clinical anaesthesiology     Volume:  24     ISSN:  1521-6896     ISO Abbreviation:  Best Pract Res Clin Anaesthesiol     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-07-08     Completed Date:  2010-07-22     Revised Date:  2011-04-28    
Medline Journal Info:
Nlm Unique ID:  101121446     Medline TA:  Best Pract Res Clin Anaesthesiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  183-97     Citation Subset:  IM    
Department of Anaesthesiology, Hospital Privado de Comunidad, Mar del Plata, Argentina.
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MeSH Terms
Anesthesia, General / adverse effects*,  methods
Continuous Positive Airway Pressure / methods
Intraoperative Complications / etiology,  prevention & control*
Lung Compliance
Oxygen / metabolism
Positive-Pressure Respiration / methods
Postoperative Complications / etiology,  prevention & control
Pulmonary Atelectasis / complications,  etiology,  prevention & control*
Pulmonary Gas Exchange
Respiratory Function Tests
Reg. No./Substance:

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