Document Detail

Prevention or reversal of atherosclerosis: review of current evidence.
MedLine Citation:
PMID:  2650523     Owner:  NLM     Status:  MEDLINE    
Treatment with lipid-reducing agents is associated with reduced morbidity and mortality from coronary heart disease. Such treatment appears to work at the level of the atherosclerotic lesion, causing stabilization, slowed progression and, in some cases, regression of lesions. Morbidity and mortality studies of cholestyramine and gemfibrozil treatment have shown that a reduction of lipid levels was associated with reduced mortality from coronary heart disease; niacin treatment has been shown to have long-term effects on reducing cardiovascular mortality. Angiographic studies have documented that beneficial effects of treatment with lipid-reducing agents and intensive computer-assisted diet counseling occur at the level of the coronary atherosclerotic lesion.
D H Blankenhorn
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The American journal of cardiology     Volume:  63     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1989 May 
Date Detail:
Created Date:  1989-05-24     Completed Date:  1989-05-24     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  38H-41H     Citation Subset:  AIM; IM    
Department of Medicine, University of Southern California School of Medicine, Los Angeles 90033.
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MeSH Terms
Antilipemic Agents / therapeutic use*
Coronary Artery Disease / epidemiology,  mortality,  prevention & control*
Reg. No./Substance:
0/Antilipemic Agents

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