Document Detail

Prevention of involutional bone loss by exercise.
MedLine Citation:
PMID:  686549     Owner:  NLM     Status:  MEDLINE    
To ascertain whether exercise could prevent involutional bone loss, we studied 18 postmenopausal women, half of whom exercised for 1 h three times a week. Total and regional bone mass were measured before and after 1 year of exercise by the techniques of total-body neutron activation analysis (total body calcium) and photon absorptiometry (bone mineral content) of the distal radius. Total body potassium was measured by whole body counting. Bone mineral content and total body potassium did not change significantly in either group. Total body calcium increased in the exercise group from 781 +/- 95 g of 801 +/- 118 g (SD). In contrast, total body calcium decreased in each subject in the sedentary group. The daily calcium balance derived from the difference in total body calcium measurements was significantly different in the two groups of women (P less than 0.001). These data support the hypothesis that exercise can modify involutional bone loss.
J F Aloia; S H Cohn; J A Ostuni; R Cane; K Ellis
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Annals of internal medicine     Volume:  89     ISSN:  0003-4819     ISO Abbreviation:  Ann. Intern. Med.     Publication Date:  1978 Sep 
Date Detail:
Created Date:  1978-10-27     Completed Date:  1978-10-27     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0372351     Medline TA:  Ann Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  356-8     Citation Subset:  AIM; IM; S    
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MeSH Terms
Bone and Bones / analysis
Calcium / analysis
Middle Aged
Minerals / analysis
Osteoporosis / prevention & control*
Physical Exertion*
Potassium / analysis
Reg. No./Substance:
0/Minerals; 7440-09-7/Potassium; 7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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