| Prevention of food allergies. | |
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MedLine Citation:
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PMID: 6150664 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Any rational approach to the prevention of food allergies must be based on the diversity of mechanisms which are involved in their pathogenesis. In addition to the IgE-mediated disorders which appear to be responsible for the largest number of cases, other immunologic (e.g., immune complex) and non-immunologic (e.g., enzymatic deficiencies) mechanisms appear to be involved. A preventive program should begin with a recognition that a potential problem exists and the identification of the individual at risk. This is accomplished by a careful documentation of IgE or other allergic reactivity in the individual or in family members. The prevention of intrauterine or postnatal sensitization is achieved by reduction in antigen transfer to the infant by maternal avoidance of potentially allergic foods in the last trimester and during lactation and by a restrictive infant diet. During the first years of infancy the encouragement of breast-feeding provides the dual benefit of eliminating one of the most common sensitizing food antigens, i.e., cow's milk protein, and providing passive s-IgA. The use of appropriate pharmacologic agents, e.g., cromolyn, may be yet another valuable adjunct in the prevention of food allergy. |
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Authors:
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J A Bellanti |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Annals of allergy Volume: 53 ISSN: 0003-4738 ISO Abbreviation: Ann Allergy Publication Date: 1984 Dec |
Date Detail:
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Created Date: 1985-01-18 Completed Date: 1985-01-18 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372346 Medline TA: Ann Allergy Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 683-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antigen-Antibody Complex
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immunology Antigens / immunology Breast Feeding Cromolyn Sodium / therapeutic use Desensitization, Immunologic Digestion Female Food Hypersensitivity / diet therapy, drug therapy, genetics, immunology, prevention & control* Histamine H1 Antagonists / therapeutic use Humans Immunity, Cellular Immunoglobulin A / immunology Immunoglobulin A, Secretory / immunology Immunoglobulin E / immunology Infant Infant, Newborn Intestinal Absorption Lactation Maternal-Fetal Exchange Pregnancy Risk |
| Chemical | |
Reg. No./Substance:
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0/Antigen-Antibody Complex; 0/Antigens; 0/Histamine H1 Antagonists; 0/Immunoglobulin A; 0/Immunoglobulin A, Secretory; 15826-37-6/Cromolyn Sodium; 37341-29-0/Immunoglobulin E |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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