Document Detail


Prevention of early mutans streptococci transmission in infants by professional tooth cleaning and chlorhexidine varnish treatment of the mother.
MedLine Citation:
PMID:  12399698     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Mutans streptococci (MS) are transmitted in early childhood from the mother to the infant, mostly by saliva. This study evaluated the influence of chlorhexidine (CHX) varnish-mediated suppression of MS in mothers with high salivary MS counts on the frequency of MS colonization in their children at 2 years of age. Professional tooth cleaning followed by CHX varnish application in 16 mothers with high salivary MS counts resulted in a significantly lower number of MS-colonized infants at 2 years of age when compared to a control group of 13 untreated mother-child pairs with high maternal salivary MS levels. The frequency of MS colonization in the CHX-treated group was not significantly different from the one found in a negative control group of 15 mother-child pairs with low maternal salivary MS levels.
Authors:
Vivian C Gripp; Ulrich Schlagenhauf
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Caries research     Volume:  36     ISSN:  0008-6568     ISO Abbreviation:  Caries Res.     Publication Date:    2002 Sep-Oct
Date Detail:
Created Date:  2002-10-25     Completed Date:  2003-02-25     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0103374     Medline TA:  Caries Res     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  366-72     Citation Subset:  D; IM    
Copyright Information:
Copyright 2002 S. Karger AG, Basel
Affiliation:
Department of Conservative Dentistry and Periodontology, School of Dental Medicine, University of Tübingen, Germany.
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MeSH Terms
Descriptor/Qualifier:
Adult
Anti-Infective Agents, Local / administration & dosage*
Chi-Square Distribution
Chlorhexidine / administration & dosage*
Colony Count, Microbial
Dental Prophylaxis
Female
Humans
Infant
Infant, Newborn
Infectious Disease Transmission, Vertical / prevention & control*
Mothers
Paint
Saliva / microbiology
Statistics, Nonparametric
Streptococcal Infections / prevention & control*,  transmission*
Streptococcus mutans / drug effects
Chemical
Reg. No./Substance:
0/Anti-Infective Agents, Local; 55-56-1/Chlorhexidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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