| Prevention and cure of rheumatoid arthritis: is it possible? | |
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MedLine Citation:
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PMID: 20534369 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Advances in treatment of rheumatoid arthritis have made it possible to profoundly influence signs and symptoms as well as the course of joint destruction in inflammatory arthritis. Earlier and more efficient treatment appears to significantly improve the prognosis of this disease. Despite these advances, cure (the absence of signs and symptoms without further treatment) is still relatively rare, observable in, at most, 20% of the patients. Remission (or a state of very low disease activity), however, has been observed with intense and individually tailored treatment in up to 75% of patients. The use of structured assessments followed by individual modification of the intensity of treatment aiming for remission leads to better clinical responses and radiological outcomes. It remains to be seen whether earlier and more aggressive treatment of patients with not yet 'fully established' rheumatoid arthritis may succeed in preventing at least some of them from progressing to destructive arthritis. |
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Authors:
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Klaus P Machold |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Best practice & research. Clinical rheumatology Volume: 24 ISSN: 1532-1770 ISO Abbreviation: Best Pract Res Clin Rheumatol Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-06-10 Completed Date: 2010-09-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101121149 Medline TA: Best Pract Res Clin Rheumatol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 353-61 Citation Subset: IM |
Copyright Information:
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Copyright 2009 Elsevier Ltd. All rights reserved. |
Affiliation:
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Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Währinger Gürtel 18-20, A-1090 Vienna, Austria. Klaus.machold@meduniwien.ac.at |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Arthritis, Rheumatoid
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diagnosis,
prevention & control*,
rehabilitation* Disease-Free Survival* Drug Administration Schedule Humans Quality of Life Remission Induction Secondary Prevention* Tertiary Prevention* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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