Document Detail


Prevention of atherosclerosis with dietary antioxidants: fact or fiction?
MedLine Citation:
PMID:  8642434     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The notion that oxidation of lipids and lipoproteins may contribute to the pathogenesis of atherosclerosis is supported by a large body of evidence. It is hypothesized that dietary antioxidants may help prevent development and progression of atherosclerosis. The available evidence helps substantiate this hypothesis but is not yet conclusive. The results of several ongoing large randomized intervention trials will provide valuable information about the efficacy and safety of supplemental dietary antioxidants in prevention of atherosclerosis.
Authors:
P B Duell
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  The Journal of nutrition     Volume:  126     ISSN:  0022-3166     ISO Abbreviation:  J. Nutr.     Publication Date:  1996 Apr 
Date Detail:
Created Date:  1996-07-16     Completed Date:  1996-07-16     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0404243     Medline TA:  J Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1067S-71S     Citation Subset:  IM    
Affiliation:
Division of Endocrinology, Diabetes and Nutrition, Oregon Health Sciences University, Portland, OR 97201-3098, USA.
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MeSH Terms
Descriptor/Qualifier:
Antioxidants / pharmacology*
Arteriosclerosis / prevention & control*
Ascorbic Acid / pharmacology
Carotenoids / pharmacology
Clinical Trials as Topic
Flavonoids / pharmacology
Humans
Selenium / pharmacology
Vitamin E / pharmacology
Grant Support
ID/Acronym/Agency:
RR 00334/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
0/Antioxidants; 0/Flavonoids; 1406-18-4/Vitamin E; 36-88-4/Carotenoids; 50-81-7/Ascorbic Acid; 7782-49-2/Selenium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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