Document Detail

Prevention of allergic diseases and IgE dosification in cord sera.
MedLine Citation:
PMID:  2088099     Owner:  NLM     Status:  MEDLINE    
In 1986, a Program on Prevention of Allergic Diseases was initiated in our country which was possible on account of the organization conditions of our health system. The program includes IgE measurement in umbilical cord serum by means of an ultramicroanalytic technique for IgE quantification. This is an heterogeneous sandwich-type immunoassay that requires only 10 microliters of reactive on each reaction step and its processing is carried out on the Cuban SUMA equipment. Two groups of children were selected and followed-up: group I included 80 one-year-old infants and group II included 60 18-months-old infants. Both groups followed hypoallergenic diets and had minimal exposure to aeroallergens within their microenvironment. Results were compared with those of respective control groups. Compliance of both groups with the prophylactic measures brought about a reduction in the existence of allergic diseases and a comparison with the control groups offered a statistically significant difference (p less than 0.001). Similarly, incidence of asthma was found more reduced in groups I and II than in the control groups (p less than 0.001). Within the groups treated under the Program on Prevention of Allergic Diseases, IgE values were lower, while the control groups exhibited a higher number of infants with figures of 200 IU/ml or more (p less than 0.05). Our results support the usefulness of preventive measures in avoiding the presence of atopic diseases.
D Fabré; H Horta; R L Solís; G Díez; J P Escobar; F Barrios; A Jústiz
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Allergologia et immunopathologia     Volume:  18     ISSN:  0301-0546     ISO Abbreviation:  Allergol Immunopathol (Madr)     Publication Date:    1990 Nov-Dec
Date Detail:
Created Date:  1991-05-20     Completed Date:  1991-05-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370073     Medline TA:  Allergol Immunopathol (Madr)     Country:  SPAIN    
Other Details:
Languages:  eng     Pagination:  309-13     Citation Subset:  IM    
Juan Manuel Márquez Pediatric Hospital, Havana, Cuba.
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MeSH Terms
Asthma / prevention & control
Environmental Exposure
Fetal Blood / immunology*
Hypersensitivity, Immediate / diagnosis,  prevention & control*
Immunoglobulin E / analysis*
Infant Care
Infant Food
Infant, Newborn
Patient Compliance
Reg. No./Substance:
37341-29-0/Immunoglobulin E

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