| Preventing ruptured ectopic pregnancy with a single serum progesterone. | |
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MedLine Citation:
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PMID: 2660569 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Retrospective data on patients with documented ectopic pregnancies have demonstrated the potential usefulness of serum progesterone in decreasing the time to diagnosis. We report a prospective trial utilizing serum progesterone in the emergency department of a large city-county hospital. Sixty-seven ectopic pregnancies were document in the 582 patients screened; 54 (80.6%) had a progesterone level less than 15 ng/ml. Only one (1.5%) ruptured ectopic pregnancy was associated with a progesterone level greater than 25 ng/ml. There were 387 documented or presumed normal intrauterine pregnancies, 41 (10.6%) had progesterone concentrations of less than 15 ng/ml and 236 (61%) had a progesterone level greater than 25 ng/ml. We decreased minimum time of diagnosis from 48 to 72 hours to less than 24 hours by use of a progesterone screening protocol. During this time the percentage of ruptured ectopic pregnancies decreased from 79.2% to 38.8% (p less than 0.05). Because of its simple interpretation and 24-hour maximum delay, we conclude that the determination of serum progesterone should be used for ectopic pregnancy screening in all patients at risk for ectopic pregnancy, or at any time when the diagnosis is in question. |
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Authors:
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T G Stovall; F W Ling; B J Cope; J E Buster |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 160 ISSN: 0002-9378 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 1989 Jun |
Date Detail:
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Created Date: 1989-07-20 Completed Date: 1989-07-20 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1425-8; discussion 1428-31 Citation Subset: AIM; IM; J |
Affiliation:
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Department of Obstetrics and Gynecology, University of Tennessee, Memphis. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Algorithms Diagnosis, Differential Female Humans Pregnancy Pregnancy Tests Pregnancy, Ectopic / blood, complications, diagnosis* Progesterone / blood* Retrospective Studies Rupture, Spontaneous Time Factors Ultrasonography |
| Chemical | |
Reg. No./Substance:
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57-83-0/Progesterone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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