| Preventing mother-to-child transmission of HIV: practical strategies for developing countries. | |
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MedLine Citation:
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PMID: 10808607 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The HIV pandemic has greatly affected women of childbearing age in developing countries and, thus, their offspring, through mother-to-child transmission (MTCT) of the virus. Scientific advances, most of them established by randomized clinical trials, have recently led to the development of practical strategies aiming to reduce the public health burden of MTCT of HIV. These advances came first in non-breast-feeding populations, for example, in Thailand and, more recently, in African populations, where breast-feeding remains the predominant mode of infant feeding. This article reviews major accomplishments in this area, outlines practical issues for program implementation, and suggests future research needs. Short-course zidovudine and short-course nevirapine in the peripartum period currently represent 2 valid options to reduce MTCT of HIV in developing countries if appropriate prenatal, obstetrical, and postnatal care is provided and if alternatives to breast-feeding are considered according to the local situation and the mother's individual decision. |
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Authors:
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F Dabis; V Leroy |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The AIDS reader Volume: 10 ISSN: 1053-0894 ISO Abbreviation: AIDS Read Publication Date: 2000 Apr |
Date Detail:
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Created Date: 2000-07-06 Completed Date: 2000-07-06 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 9206753 Medline TA: AIDS Read Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 241-4 Citation Subset: X |
Affiliation:
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INSERM unit U.330, Institut de Santé Publique, Epidémiologie et Développement (ISPED), Université Victor Segalen, Bordeaux, France. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anti-HIV Agents
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therapeutic use* Breast Feeding / adverse effects Clinical Trials as Topic Developing Countries* Drug Therapy, Combination Female HIV Infections / drug therapy*, prevention & control, transmission* Humans Infant Infant, Newborn Infectious Disease Transmission, Vertical / prevention & control* Pregnancy Pregnancy Complications, Infectious / drug therapy |
| Chemical | |
Reg. No./Substance:
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0/Anti-HIV Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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