Document Detail

Prevalence of wine intolerance: results of a survey from Mainz, Germany.
MedLine Citation:
PMID:  22787508     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Wine is an ancient food product, ubiquitous across cultures all over the world. Its effects on health have been extensively studied, yet there have been only a few case reports of wine intolerance or wine allergy. We studied the prevalence of self-reported wine intolerance in the adult population of Mainz, Germany.
METHODS: In 2010, a questionnaire-based cross-sectional study was conducted to assess the prevalence of wine intolerance among adults in Mainz, a city in the wine-cultivating area of Rhine-Hesse. 4000 persons randomly chosen from population lists were asked to fill out a questionnaire about their alcohol intake and the occurrence of various intolerance reactions and allergy-like symptoms after drinking wine.
RESULTS: Of the 4000 who received the questionnaire, 948 (23.7%) filled it out and returned it to us. 68 (7.2% of respondents) reported intolerance to wine and/or allergy-like symptoms after drinking wine. Self-reported wine intolerance was more prevalent in women than in men (8.9% vs. 5.2%, p = 0.026). Wine-intolerant persons also more commonly reported intolerance to beer and alcohol in general. Allergy-like symptoms were more common after the consumption of red wine. The most commonly reported reactions to wine were cutaneous flushing, itch, and nasal congestion.
CONCLUSION: Wine intolerance was found to be more common than expected. The data reported here are less suggestive of an immunologically mediated allergy than of intolerance to alcohol, biogenic amines, or other ingredients of wine.
Petra Wigand; Maria Blettner; Joachim Saloga; Heinz Decker
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2012-06-22
Journal Detail:
Title:  Deutsches Ärzteblatt international     Volume:  109     ISSN:  1866-0452     ISO Abbreviation:  Dtsch Arztebl Int     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-07-12     Completed Date:  2012-11-26     Revised Date:  2013-07-12    
Medline Journal Info:
Nlm Unique ID:  101475967     Medline TA:  Dtsch Arztebl Int     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  437-44     Citation Subset:  IM    
Institute of Molecular Biophysics of the Johannes Gutenberg University Mainz.
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MeSH Terms
Alcohol Drinking / epidemiology*
Food Hypersensitivity / epidemiology*
Germany / epidemiology
Health Surveys
Risk Assessment
Wine / utilization*
Comment In:
Dtsch Arztebl Int. 2013 Jan;110(3):39   [PMID:  23413379 ]
Dtsch Arztebl Int. 2013 Jan;110(3):39-40   [PMID:  23413381 ]
Dtsch Arztebl Int. 2013 Jan;110(3):39   [PMID:  23413380 ]
Dtsch Arztebl Int. 2013 Jan;110(3):40   [PMID:  23413382 ]

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