| Prevalence of vitamin D deficiency in adult tuberculosis patients at a central hospital in Malawi. | |
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MedLine Citation:
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PMID: 21333112 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Vitamin D deficiency (VDD) is associated with impaired mycobacterial immunity and susceptibility to tuberculosis (TB). We measured 25 hydroxy vitamin D levels in 161 adult TB patients at a central hospital in Malawi, of whom 120 (74.5%) had ≤75 nmol/l (hypovitaminosis D), 68 (42%) had ≤50 nmol/l (VDD) and 13.6% of in-patients and 6.8% of out-patients had ≤25 nmol/l (severe VDD). In-patients had lower body mass index (BMI; 19.0 vs. 20.5, P < 0.004), and vitamin D levels were lower in those with BMI < 20. However, on multiple regression analysis in-patient status and BMI were not associated with vitamin D level. We conclude that VDD is common in adult TB patients in Malawi. In this small sample, it was not possible to identify any independent associations of VDD. |
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Authors:
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R Banda; B Mhemedi; T J Allain |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease Volume: 15 ISSN: 1815-7920 ISO Abbreviation: Int. J. Tuberc. Lung Dis. Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-02-21 Completed Date: 2011-06-20 Revised Date: 2011-08-25 |
Medline Journal Info:
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Nlm Unique ID: 9706389 Medline TA: Int J Tuberc Lung Dis Country: France |
Other Details:
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Languages: eng Pagination: 408-10 Citation Subset: IM |
Affiliation:
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College of Medicine, University of Malawi, Blantyre, Malawi. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Body Mass Index Cross-Sectional Studies Female Hospitals / statistics & numerical data Humans Malawi / epidemiology Male Middle Aged Prevalence Regression Analysis Tuberculosis / epidemiology* Vitamin D / analogs & derivatives*, blood Vitamin D Deficiency / complications, epidemiology* Young Adult |
| Grant Support | |
ID/Acronym/Agency:
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//Wellcome Trust |
| Chemical | |
Reg. No./Substance:
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1406-16-2/Vitamin D; 64719-49-9/25-hydroxyvitamin D |
| Comments/Corrections | |
Comment In:
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Int J Tuberc Lung Dis. 2011 Aug;15(8):1133-4
[PMID:
21740682
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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