Document Detail

Prevalence of unrecognized lower extremity peripheral arterial disease and the associated factors in chinese hypertensive adults.
MedLine Citation:
PMID:  23146365     Owner:  NLM     Status:  In-Data-Review    
We aimed to examine the prevalence of lower-extremity peripheral artery disease (LE-PAD) and its associated factors in 3,128 Chinese hypertensive adults 45 to 75 years old without known cardiovascular disease, PAD, chronic kidney disease, diabetes, and dyslipidemia. A cross-sectional investigation was carried out in a rural area of Lianyungang, China. An ankle-brachial index ≤0.90 in either leg was used to define LE-PAD. Prevalence of LE-PAD was 9.0% (10.0% in women and 7.4% in men). In the multivariable logistic regression model, odds ratios (95% confidence interval) of having LE-PAD, were 1.82 (1.27 to 2.61) for participants 65 to 75 versus 45 to 55 years old, 1.48 (1.00 to 1.20) for participants with a waist circumference ≥90 versus <90 cm, 1.47 (1.05 to 2.04) and 1.62 (1.15 to 2.27) for participants with grade 2 and 3 hypertension versus controlled blood pressure or grade 1 hypertension, 1.35 (1.00 to 1.83) and 1.61 (1.16 to 2.23) for participants with heart rate at rest 70 to 80 and ≥80 versus <70 beats/min, and 1.41 (1.00 to 1.97) for participants with poor versus good sleeping quality. For other risk factors, gender-related differences were observed. Adjusted odds ratios of having LE-PAD for men and women were 1.07 (0.66 to 1.74) and 0.65 (0.47 to 0.90) for inland versus coastal residents and 1.03 (0.57 to 1.86) and 1.62 (1.09 to 2.41) for participants with body mass index ≥25 versus <25 kg/m(2). In conclusion, there was a high prevalence of LE-PAD in Chinese hypertensive adults without known cardiovascular disease, PAD, chronic kidney disease, diabetes, and dyslipidemia, particularly in women in coastal areas and in participants with higher heart rate and poor sleeping quality. Therefore, ankle-brachial index determinations should be encouraged in clinical practice in Chinese hypertensive adults.
Mingli He; Xianhui Qin; Yimin Cui; Yefeng Cai; Liming Sun; Xin Xu; Binyan Wang; Genfu Tang; Houxun Xing; Xiaobin Wang; Xiping Xu; Yong Huo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  110     ISSN:  1879-1913     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-11-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1692-8     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Department of Neurology, First People's Hospital of Lianyungang City, Lianyungang, China.
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