| Prevalence and significance of an isolated long QT interval in elite athletes. | |
| | |
MedLine Citation:
|
PMID: 17947213 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
AIMS: Identification of a prolonged, corrected QT (QTc) interval in athletes may be a recommendation for disqualification from competitive sports. However, the prevalence and diagnostic significance of an isolated prolonged QTc in asymptomatic athletes without familial disease is unknown. METHODS AND RESULTS: Between 1996 and 2006, 2000 elite athletes (mean age, 20.2 years) underwent 12-lead ECG and 2-D echocardiography. The QT interval was corrected for heart rate (QTc). Athletes with QTc > 460 ms underwent 48 h Holter monitor and an exercise stress test. All athletes with a prolonged QTc interval were offered genetic testing and first-degree relatives were invited for ECG. The QTc was prolonged in seven (0.4%) athletes ranging from 460 to 570 ms. Three athletes had a QTc value of >500 ms and all exhibited one of: paradoxical prolongation of QTc during exercise, a confirmatory genetic mutation, or prolonged QTc in a first-degree relative. In contrast, none of the athletes with a QTc value of <500 ms had any other features to indicate long QT syndrome (LQTS). CONCLUSION: The prevalence of prolonged QTc in elite athletes is 0.4%. A QTc of >500 ms is highly suggestive of LQTS. A QTc of <500 ms in the absence of symptoms or familial disease is unlikely to represent LQTS in elite athletes. |
| | |
Authors:
|
Sandeep Basavarajaiah; Matthew Wilson; Gregory Whyte; Ajay Shah; Elijah Behr; Sanjay Sharma |
Related Documents
:
|
8621373 - The incidence of exercise-induced bronchospasm in competitive figure skaters. 16604143 - Symposium overview. dietary reference intakes: considerations for physical activity. 10589473 - Equine respiratory pharmacology. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2007-10-18 |
Journal Detail:
|
Title: European heart journal Volume: 28 ISSN: 0195-668X ISO Abbreviation: Eur. Heart J. Publication Date: 2007 Dec |
Date Detail:
|
Created Date: 2007-12-06 Completed Date: 2008-04-10 Revised Date: 2008-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 8006263 Medline TA: Eur Heart J Country: England |
Other Details:
|
Languages: eng Pagination: 2944-9 Citation Subset: IM |
Affiliation:
|
University Hospital Lewisham/King's College Hospital, London SE5 9RS, UK. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Electrocardiography / methods Exercise Test Female Heart Rate / physiology* Humans Long QT Syndrome / diagnosis*, epidemiology, genetics Male Prevalence Sports / physiology* |
| Comments/Corrections | |
Comment In:
|
Eur Heart J. 2007 Dec;28(23):2825-6
[PMID:
17967824
]
Eur Heart J. 2008 May;29(9):1210-1; author reply 1211 [PMID: 18411211 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Diabetes mellitus and risk of fatal ischaemic heart disease by gender: 18 years follow-up of 74,914 ...
Next Document: Cardiac beta-myosin heavy chain defects in two families with non-compaction cardiomyopathy: linking ...