Document Detail


Prevalence and significance of isolated fetal choroid plexus cysts detected in early pregnancy by transvaginal sonography in women of advanced maternal age.
MedLine Citation:
PMID:  10215069     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study examines the prevalence of isolated fetal choroid plexus cysts (CPCs) detected in early pregnancy by transvaginal sonography in an increased genetic risk population and their association with abnormal fetal karyotype. A prospective study was performed on 1692 pregnant women (>37 years) who underwent transvaginal scan at 11-16 weeks' gestation before genetic amniocentesis. The prevalence of isolated CPCs in our population was 1.48 per cent. An abnormal fetal karyotype was found in one case (4 per cent). It was concluded that if fetal CPCs are apparently isolated, genetic amniocentesis is not mandatory and additional risk factors such as advanced maternal age should be the main indication for fetal karyotyping.
Authors:
L Guariglia; P Rosati
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Prenatal diagnosis     Volume:  19     ISSN:  0197-3851     ISO Abbreviation:  Prenat. Diagn.     Publication Date:  1999 Feb 
Date Detail:
Created Date:  1999-06-22     Completed Date:  1999-06-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8106540     Medline TA:  Prenat Diagn     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  128-31     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynaecology, Catholic University of the Sacred Heart, Rome, Italy.
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MeSH Terms
Descriptor/Qualifier:
Adult
Amniocentesis
Aneuploidy
Brain Diseases / embryology,  epidemiology,  genetics,  ultrasonography*
Case-Control Studies
Choroid Plexus*
Cysts / embryology,  epidemiology,  genetics,  ultrasonography*
Female
Fetal Diseases / embryology,  epidemiology,  genetics,  ultrasonography*
Humans
Italy / epidemiology
Karyotyping
Maternal Age
Middle Aged
Pregnancy
Pregnancy Trimester, First
Pregnancy, High-Risk
Prevalence
Prospective Studies
Retrospective Studies
Ultrasonography, Prenatal*
Vagina

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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