Document Detail

Prevalence and severity of echocardiographic left ventricular hypertrophy in hypertensive patients in clinical practice.
MedLine Citation:
PMID:  20825358     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND AIM: The prevalence of left ventricular hypertrophy (LVH) in human hypertension has been mostly documented in population-based samples and selected hypertensive cohorts. Rather scant data are available from clinical practice. Thus, we examined the prevalence of LVH in a large group of hypertensive patients referred by general practitioners to a routine echocardiographic examination.
METHODS: A total of 2249 hypertensive subjects (mean age 62 years, 52.3% men, 84.5% treated) referred by their practitioners to 17 outpatient echocardiographic laboratories across Italy for detection of hypertensive early cardiac damage were included in the study. LVH was defined as left ventricular mass (A) ≥ 225/163 g, (B) ≥ 116/96 g/m(2), (C) ≥ 49/45 g/m(2.7) in men/women, respectively; LVH was graded as mild, moderate and severe according to Lang's report.
RESULTS: Overall, patients with LVH were 58%, 58% and 65% by criteria A, B and C, respectively. LVH was mild in 33% (A), 36% (B) and 29% (C), moderate in 31% (A), 28% (B) and 27% (C), and severe in 36% (A), 36% (B) and 44% (C).
CONCLUSIONS: Data provided by this multicentre nationwide survey support the view that, despite therapeutic interventions, LVH remains a highly frequent phenotype in human hypertension and that severe LVH is present in a large fraction of hypertensives.
Cesare Cuspidi; Francesca Negri; Maria Lorenza Muiesan; Anna Capra; Laura Lonati; Alberto Milan; Carla Sala; Marcella Longo; Alberto Morganti;
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Publication Detail:
Type:  Journal Article     Date:  2010-09-09
Journal Detail:
Title:  Blood pressure     Volume:  20     ISSN:  1651-1999     ISO Abbreviation:  Blood Press.     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-01-21     Completed Date:  2011-05-31     Revised Date:  2012-03-30    
Medline Journal Info:
Nlm Unique ID:  9301454     Medline TA:  Blood Press     Country:  England    
Other Details:
Languages:  eng     Pagination:  3-9     Citation Subset:  IM    
Department of Clinical Medicine and Prevention, University of Milano-Bicocca, Milan, Italy.
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MeSH Terms
Blood Pressure
Cross-Sectional Studies
General Practitioners
Hypertension / epidemiology,  physiopathology*,  ultrasonography
Hypertrophy, Left Ventricular / epidemiology,  physiopathology*,  ultrasonography
Italy / epidemiology
Middle Aged
Severity of Illness Index

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