Document Detail

Prevalence of sensitization reported and objectively assessed food hypersensitivity amongst six-year-old children: a population-based study.
MedLine Citation:
PMID:  16846454     Owner:  NLM     Status:  MEDLINE    
There is a paucity of information on food hypersensitivity (FHS) in young children and there are even fewer population-based studies in this area. The aim of the study was to determine the prevalence of parentally reported FHS, and objectively diagnosed FHS amongst six-year-old children and to establish the rates of sensitization to key allergens. This population-based cohort study recruited 798 6-year-olds resident on the Isle of Wight (UK). Sensitization rates, reported rates of FHS and objectively assessed FHS was established using food challenges. A total of 94 (11.8%) 6 yr olds reported a problem with a food or food ingredient. The rate of sensitization to the pre-defined panel of food allergens was 25/700 (3.6%). Based on open food challenge and/or suggestive history and skin tests, the prevalence of FHS was 2.5% (95% CI 1.5-3.8). Based on double-blind challenges, a clinical diagnosis or suggestive history and positive skin tests, the prevalence was 1.6% (95% CI 0.9-2.7). The rates of perception of FHS are higher than the prevalence of sensitization to main food allergens and the prevalence of FHS based on food challenges. Milk, peanut and wheat were the key food allergens amongst those with positive challenges.
Carina Venter; Brett Pereira; Jane Grundy; C B Clayton; S H Arshad; Taraneh Dean
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology     Volume:  17     ISSN:  0905-6157     ISO Abbreviation:  Pediatr Allergy Immunol     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-07-18     Completed Date:  2006-09-19     Revised Date:  2014-03-17    
Medline Journal Info:
Nlm Unique ID:  9106718     Medline TA:  Pediatr Allergy Immunol     Country:  England    
Other Details:
Languages:  eng     Pagination:  356-63     Citation Subset:  IM    
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MeSH Terms
Food Hypersensitivity / epidemiology*,  immunology*
Great Britain / epidemiology
Milk Hypersensitivity / epidemiology,  immunology
Peanut Hypersensitivity / epidemiology,  immunology
Wheat Hypersensitivity / epidemiology,  immunology
Grant Support
PDF/01/055//Department of Health

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