Document Detail


Prevalence and risk factors of obstructive sleep apnea among middle-aged urban Indians: a community-based study.
MedLine Citation:
PMID:  19307155     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The epidemiology of obstructive sleep apnea (OSA) and obstructive sleep apnea syndrome (OSAS) is not well studied among Indians. We sought to determine the prevalence and risk factors of OSA in a middle-aged urban Indian population. METHODS: We conducted a two-stage, cross-sectional, community-based study in four different socioeconomic zones of the South Delhi district, India, from April 2005 to June 2007. In stage 1, subjects of either gender aged 30-65 yrs were administered a questionnaire by door-to-door survey using systematic random sampling. Subjects that responded were classified as habitual and non-habitual snorers. In stage 2, all the habitual and 10% of randomly selected non-habitual snorers were invited for overnight polysomnographic study. RESULTS: Of the 2860 subjects approached, 2505 (88%) completed stage 1. Habitual snoring was present in 452 (18%) subjects. In stage 2, OSA defined as apnea-hypopnea index 5 was observed in 94 (32.4%) of 290 habitual snorers and 3 (4%) of 75 non-habitual snorers. Estimated population prevalence of OSA and OSAS was 9.3% (95% CI 8.2-10.5%) and 2.8% (2.1-3.4%) respectively. On multivariable analysis, male gender (adjusted odds ratio 3.8 [1.7-4.9]), body-mass index 25 kg/m(2) (4.1 [2.0-8.3]), and abdominal obesity (2.2 [1.9-5.3]) were independently associated with the presence of OSA. A linear trend was observed in the prevalence of OSA across the socioeconomic strata. CONCLUSIONS: OSA is a significant public health problem in the middle-aged Indian population across the socioeconomic spectrum. OSA is associated with some of the well known risk factors for cardiovascular disease.
Authors:
Emmadi V Reddy; Tamilarasu Kadhiravan; Hemant K Mishra; Vishnubhatla Sreenivas; Kumud K Handa; Sanjeev Sinha; Surendra K Sharma
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-03-23
Journal Detail:
Title:  Sleep medicine     Volume:  10     ISSN:  1878-5506     ISO Abbreviation:  Sleep Med.     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-08-24     Completed Date:  2009-12-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100898759     Medline TA:  Sleep Med     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  913-8     Citation Subset:  IM    
Affiliation:
Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
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MeSH Terms
Descriptor/Qualifier:
Adult
Age Distribution
Aged
Cross-Sectional Studies
Female
Humans
India / epidemiology
Male
Middle Aged
Obesity / epidemiology
Polysomnography
Prevalence
Residence Characteristics
Risk Factors
Sex Distribution
Sleep Apnea, Obstructive / epidemiology*
Urban Population / statistics & numerical data*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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