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Prevalence and risk factors of asymptomatic bacteriuria among pregnant Nigerian infected with HIV.
MedLine Citation:
PMID:  23186370     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract Objective: There are conflicting report on the association of HIV infection and asymptomatic bacteriuria (ASB). Most of these studies were from areas with low HIV burden. This study determined the prevalence and risk factors of ASB in HIV positive pregnant women. Methods: A cross sectional study among HIV positive pregnant women seen at a large PMTCT clinic in Lagos Nigeria. The women were evaluated for ASB at first clinic attendance. Blood samples were also collected for viral load, CD4 count and haemoglobin levels assessment. Data were managed with SPSS for windows version 19. Results: 102(18.1%) women out of 563 studied were found positive for asymptomatic bacteriuria. Ninety seven (95.1%) of the positive samples yielded single bacterial isolates. Escherichia.coli (44.3%) and Proteus mirabilis (21.6%) were the most common bacterial isolates. Previous urinary tract infection (OR:4.3), HIV-1 RNA greater than 10,000 copies/mL(OR:3.9), CD4 count< 200 cells/mm3 (OR:1.4) and maternal haemoglobin <11g/dl (OR: 1.4) were factors significantly associated with ASB after controlling for possible confounders. Conclusion: ASB is common in HIV positive pregnant women in our environment and is associated with previous UTI, high viral load, low CD4 count and maternal haemoglobin <11g/dl.
Authors:
Oliver C Ezechi; Chidinma V Gab-Okafor; David A Oladele; Olufunto O Kalejaiye; Bamidele Oke; Sabdat O Ekama; Rosemary A Audu; Rosemary N Okoye; Innocent A O Ujah
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-28
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  -     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Clinical Sciences Division, Nigerian Institute of Medical Research, Yaba, Nigeria.
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