Document Detail

Prevalence and risk factor for MDR-GNB infection in liver transplantation.
MedLine Citation:
PMID:  23276929     Owner:  NLM     Status:  MEDLINE    
Liver transplantation (LT) has emerged as a viable therapy for various end-stage liver diseases. Multi-drug resistant Gram-negative bacilli (MDR-GNB) have emerged as predominant pathogens. The prevalence of MDR-GNB infection has been increasing in LT recipients, especially in early post-LT stages. MDR-GNB infection has become a main cause of death following LT. Since key elements of MDR-GNB infection after LT mainly include the pre-LT severity of underlying disease, technical problems, acute rejection, and so on, appropriate measures, such as improvement of LT technology and management, restriction of antibiotic use and immunosuppressive therapy advancement, should be commenced to prevent and control the occurrence of MDR-GNB infection. A better understanding of the prevalence of and risk factors for MDR-GNB infection complications is needed to improve quality of life and survival rate after LT.
Lin Zhong; Tong-Yi Men; Hao Li; Yan Gu; Xin Ding; Tong-Hai Xing; Jun-Wei Fan; Zhi-Hai Peng
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2013-01-01
Journal Detail:
Title:  Frontiers in bioscience (Landmark edition)     Volume:  18     ISSN:  1093-4715     ISO Abbreviation:  Front Biosci (Landmark Ed)     Publication Date:  2013  
Date Detail:
Created Date:  2013-01-01     Completed Date:  2013-06-12     Revised Date:  2013-07-29    
Medline Journal Info:
Nlm Unique ID:  101612996     Medline TA:  Front Biosci (Landmark Ed)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  366-70     Citation Subset:  IM    
Department of General Surgery, Shanghai First People Hospital, Medical School of Shanghai Jiaotong University, 85 Wu Jing Road, 200080, Shanghai, People's Republic of China.
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MeSH Terms
Drug Resistance, Multiple, Bacterial*
Gram-Negative Bacteria / drug effects
Gram-Negative Bacterial Infections / epidemiology,  etiology*,  prevention & control
Liver Transplantation / adverse effects*
Risk Factors

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