Document Detail

Prevalence of retinopathy of prematurity: an institutional cross-sectional study of preterm infants in Brazil.
MedLine Citation:
PMID:  20058831     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Retinopathy of prematurity (ROP) is the leading cause of childhood blindness in most developed countries. This study aimed to verify ROP prevalence among all very low birth weight (VLBW) preterm infants admitted to a level-3 teaching hospital in Porto Alegre, Rio Grande do Sul, Brazil. METHODS: Institutional cross-sectional study of 407 premature infants with birth weight < or = 1,500 g or gestational age (GA) < or =32 weeks between 2002 and 2007. All infants screened for ROP were examined after the fourth week of life and followed up until the 45th week of adjusted GA. ROP prevalence was estimated at a 95% confidence level. RESULTS: Some degree of ROP in one or both eyes occurred in 25.5% (104) of all screened infants, and severe ROP (threshold stage 3 or higher, requiring treatment to prevent vision loss, as per the criteria of the U.S.-based Multicenter Trial of Cryotherapy for Retinopathy of Prematurity, CRYO-ROP) occurred in 5.8% (24). Based on the criteria of The International Classification for Retinopathy of Prematurity (ICROP, 1984/1987), the disease reached stages 1, 2, and 3 in 11.3% (46), 8.4% (34), and 5.4% (22), respectively. One infant developed the disease up to stage 4 (partial retinal detachment), and one progressed to stage 5 (complete retinal detachment, resulting in 0.2% overall prevalence for ROP-induced blindness). CONCLUSIONS: Overall incidence of ROP in this institutional study (25.5%) was comparable to international results from developed countries. A comprehensive countrywide survey on ROP in Brazil is recommended to determine any regional differences in disease prevalence.
Jo?o B Fortes Filho; Gabriela U Eckert; Fabiana B Valiatti; Marlene C da Costa; Pedro P Bonomo; Renato S Procianoy
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Revista panamericana de salud p?blica = Pan American journal of public health     Volume:  26     ISSN:  1020-4989     ISO Abbreviation:  Rev. Panam. Salud Publica     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2010-01-11     Completed Date:  2010-03-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9705400     Medline TA:  Rev Panam Salud Publica     Country:  United States    
Other Details:
Languages:  eng     Pagination:  216-20     Citation Subset:  IM    
Department of Ophthalmology, School of Medicine, Federal University of Rio Grande do Sul and Hospital de Cl?nicas de Porto Alegre, Porto Alegre, RS, Brazil.
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MeSH Terms
Brazil / epidemiology
Cross-Sectional Studies
Infant, Newborn
Infant, Very Low Birth Weight
Retinopathy of Prematurity / epidemiology*

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