Document Detail


Prevalence, relation to spontaneous closure, and association of muscular ventricular septal defects with other cardiac defects.
MedLine Citation:
PMID:  7801866     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Previous studies on muscular ventricular septal defect (VSD) have not taken into account the specific defect location in the septum. We retrospectively reviewed all patients with a muscular VSD, with and without associated malformations, diagnosed over 32 months to determine the prevalence and rate of spontaneous closure of single defects in relation to location in the muscular septum. Defects were classified into 4 groups: midmuscular, apical, anterior, and posterior. Two hundred seven patients were identified, of whom 125 had a single defect. The relative prevalence of single muscular VSD was: midmuscular 55 (44%), apical 31 (25%), anterior 33 (26%), and posterior 6 (5%). Thirty patients had signs of spontaneous closure and only 1 underwent surgery. There was no difference in rate of closure with respect to anatomic locations. Patients with multiple muscular VSD were either referred for surgery in the first year of life or had a course similar to patients with a single VSD. Muscular VSD associated with other cardiac malformations was more often encountered in patients with conoventricular VSD and coarctation of the aorta. The distribution of anatomic groups of muscular VSD in association with malformations was similar to the single VSD.
Authors:
C Ramaciotti; J M Vetter; R A Bornemeier; A J Chin
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of cardiology     Volume:  75     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1995 Jan 
Date Detail:
Created Date:  1995-01-23     Completed Date:  1995-01-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  61-5     Citation Subset:  AIM; IM    
Affiliation:
Noninvasive Laboratories, Children's Hospital of Philadelphia, Pennsylvania 19104.
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MeSH Terms
Descriptor/Qualifier:
Child, Preschool
Heart Defects, Congenital / complications*
Heart Septal Defects, Ventricular / classification,  complications*,  ultrasonography
Heart Septum / ultrasonography
Humans
Infant
Prevalence
Remission, Spontaneous
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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