| Prevalence and predictors of pulmonary hypertension in elderly patients with isolated diastolic heart failure. | |
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MedLine Citation:
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PMID: 20806196 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Despite the growing recognition that pulmonary hypertension can develop in diastolic heart failure; its clinical significance remains poorly defined. AIM: We sought to explore the prevalence and predictors of pulmonary hypertension in elderly patients with isolated diastolic heart failure. METHODS: We enrolled 100 consecutive elderly patients with isolated diastolic heart failure. All patients underwent transthoracic echocardiography to measure the pulmonary artery systolic pressure, diastolic function indices (mitral E peak deceleration time, isovolumetric relaxation time, early mitral annular diastolic velocity), left atrial diameter and left ventricular mass index. Pulmonary hypertension was defined as pulmonary artery systolic pressure > or = 37 mm Hg. We classified patients into two groups: one with diastolic heart failure and concomitant pulmonary hypertension, and one with diastolic heart failure but without concomitant pulmonary hypertension. RESULTS: The mean age of the whole series was 65.4 + or - 5.4 years, 49 (49%) being female. Patients with pulmonary hypertension (20% of the whole series) were more often females, hypertensive, more likely to have atrial fibrillation, pulmonary congestion symptoms, larger left atrial diameter, lower early mitral annular diastolic velocity, lower left ventricular ejection fraction, and more likely to have mitral regurgitation (p < 0.05 for all). Multivariate logistic regression analysis identified female gender, atrial fibrillation, and early mitral annular diastolic velocity (e') as the independent predictors of the presence of pulmonary hypertension. CONCLUSIONS: Pulmonary hypertension is fairly prevalent in elderly patients with diastolic heart failure. Female gender, atrial fibrillation, and early mitral annular diastolic velocity (e') were the independent predictors of the presence of pulmonary hypertension in this patient group. |
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Authors:
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Osama Rifaie; Hayam El-Damanhory; May Amr; Wail Nammas |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Kardiologia polska Volume: 68 ISSN: 0022-9032 ISO Abbreviation: Kardiol Pol Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-08-31 Completed Date: 2010-12-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0376352 Medline TA: Kardiol Pol Country: Poland |
Other Details:
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Languages: eng Pagination: 655-61 Citation Subset: IM |
Affiliation:
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Cardiology Department, Faculty of Medicine, Ain Shams University, Abbassia, Cairo, Egypt. |
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| MeSH Terms | |
Descriptor/Qualifier:
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Age Distribution Aged Atrial Fibrillation / epidemiology Comorbidity Echocardiography Female Heart Atria / physiopathology Heart Failure, Diastolic / epidemiology*, physiopathology Hemodynamics Humans Hypertension, Pulmonary / epidemiology*, physiopathology, ultrasonography Logistic Models Male Mitral Valve Insufficiency / epidemiology Multivariate Analysis Prevalence Sex Distribution Ventricular Dysfunction, Left / physiopathology |
| Comments/Corrections | |
Comment In:
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Kardiol Pol. 2010 Jun;68(6):662-3
[PMID:
20806197
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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