| Prevalence, predictors, and mortality significance of the causative arrhythmia in patients with electrical storm. | |
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MedLine Citation:
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PMID: 15574176 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: Electrical storm (ES) is characterized by either refractory ventricular tachycardia (VT) or ventricular fibrillation (VF). However, little is known about the prevalence, predictors, and mortality implications of the causative arrhythmia in ES. We sought to assess the prevalence, predictors, and survival significance of VT and VF as the causative arrhythmia of ES in implantable cardioverter defibrillator (ICD) patients. METHODS AND RESULTS: Consecutive patients from January 2000 to December 2002 who presented to the ICD clinic with > or = 2 separate ventricular arrhythmic episodes requiring shock within 24 hours were included in the study. ICD interrogation confirmed the number of shocks and provided electrograms for interpretation of the causative arrhythmia. Patients were grouped as VF or VT according to the causative arrhythmia. Their prevalence, predictors, and mortality rates were compared. Of 2,028 patients assessed in the ICD clinic, 208 (10%) presented with ES. VF was the cause of ES in 99 of 208 patients, for an overall prevalence of 48%. Original ICD indication, coronary artery disease, and amiodarone therapy were predictive for the causative arrhythmia. There was no mortality difference between the VT and VF groups; however, both groups had significantly increased mortality compared to a control ICD population without ES. CONCLUSION: VF is the causative arrhythmia for a sizable proportion of patients with ES. The initial ICD indication, coronary artery disease, and amiodarone therapy are predictors of the causative arrhythmias in ES. There does not appear to be any mortality difference between ES patients with VT and VF, but mortality is increased in patients with ES versus control ICD patients without ES. |
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Authors:
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Atul Verma; Fethi Kilicaslan; Nassir F Marrouche; Stephen Minor; Mohammed Khan; Oussama Wazni; J David Burkhardt; William A Belden; Jennifer E Cummings; Ahmad Abdul-Karim; Walid Saliba; Robert A Schweikert; Patrick J Tchou; David O Martin; Andrea Natale |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of cardiovascular electrophysiology Volume: 15 ISSN: 1045-3873 ISO Abbreviation: J. Cardiovasc. Electrophysiol. Publication Date: 2004 Nov |
Date Detail:
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Created Date: 2004-12-02 Completed Date: 2005-04-11 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9010756 Medline TA: J Cardiovasc Electrophysiol Country: United States |
Other Details:
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Languages: eng Pagination: 1265-70 Citation Subset: IM |
Affiliation:
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Cleveland Clinic Foundation, Section of Pacing and Electrophysiology, Cleveland, Ohio 44195, USA. |
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Arrhythmias, Cardiac / complications*, mortality Defibrillators, Implantable* / adverse effects Female Humans Male Prevalence Prognosis Recurrence Survival Analysis Tachycardia, Ventricular / etiology*, mortality Ventricular Fibrillation / etiology*, mortality |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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