Document Detail

Prevalence and prediction of left atrial thrombus in patients with a recent cerebral ischemic event, who are in sinus rhythm: a single-center experience.
MedLine Citation:
PMID:  19490373     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Left atrial thrombus (LAT) is frequently present in patients with cerebral ischemic events (CIE) who are in atrial fibrillation. The prevalence and predictor of LAT in patients who are in sinus rhythm (SR) is unclear. OBJECTIVE: To determine the prevalence and identify predictors of LAT formation in patients with CIE who are in SR. METHODS: Consecutive patients with CIE who are in SR were evaluated by transesophageal echocardiography (TEE) from July 2000 to August 2001. Patient demographics including cerebrovascular risk factors were recorded. RESULTS: LAT was present in 5.5%. Left ventricular systolic dysfunction (LVSD) was present in 25 (10%). Patients' mean age was 59 +/- 14 years and 119 (50%) were male. In the univariate analysis, LAT was associated with LVSD (odds ratio [OR] 9.24, 95% confidence interval [CI] 2.8; 10.3) and male patients (OR 4.56, 95% CI: 1.6, 12.6) who had coronary artery disease (OR 3.4, 95% CI: 1.3, 8.4). In the multivariate analysis, LVSD (OR 10.6, CI 2.2-51.6) strongly predicted the development of LAT. CONCLUSIONS: LAT is not uncommon in patients CIE, who are in sinus rhythm, especially those with poor left ventricular functions. TEE should be considered in patients with CIE and LVSD for early detection and treatment of LAT.
Abutaher M Yahia; Aasma Shaukat; Jawad F Kirmani; Julius Gene Latorre; Adnan I Qureshi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of neuroimaging : official journal of the American Society of Neuroimaging     Volume:  19     ISSN:  1552-6569     ISO Abbreviation:  J Neuroimaging     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-09-30     Completed Date:  2009-12-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9102705     Medline TA:  J Neuroimaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  323-5     Citation Subset:  IM    
Department of Neurology, Neurosurgery & Radiology, Upstate Medical University, Syracuse, NY 13210, USA.
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MeSH Terms
Aged, 80 and over
Atrial Fibrillation / epidemiology*
Brain Ischemia / epidemiology*
Coronary Artery Disease / epidemiology
Functional Laterality*
Heart Atria*
Heart Diseases / diagnosis,  epidemiology*
Middle Aged
Sex Characteristics
Thrombosis / diagnosis,  epidemiology*
Young Adult

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