Document Detail

Prevalence of postenteritis cow's milk protein intolerance.
MedLine Citation:
PMID:  3325469     Owner:  NLM     Status:  MEDLINE    
The object of this study was to ascertain the frequency of postinfectious cow's milk protein hypersensitivity (CMPH). Twenty-four infants less than 3 months old were included in the study. Following hospitalization for acute gastroenteritis, the infants were given a protein hydrolysate formula for a period of 6 weeks, after which an intestinal biopsy was performed. Thereafter, a milk challenge was given. The existence of CMPH was defined as a postchallenge reduction of one or more of the mucosal disaccharidases below the normal levels for our laboratory. A bacterial etiology of the gastroenteritis was found in 10. Nineteen infants had no adverse reaction to cow's milk after 6 weeks on a hypoallergenic formula. Only two could be confidently diagnosed as having developed secondary CMPH; both had been infected by Escherichia coli 0 111. One infant had primary CMPH and one extra-intestinal CMPH. The incidence of secondary CMPH with gastrointestinal manifestations in this series was considerably less than described elsewhere.
C Hager; J Faber; A Kaczuni; R Goldstein; E Levy; S Freier
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Israel journal of medical sciences     Volume:  23     ISSN:  0021-2180     ISO Abbreviation:  Isr. J. Med. Sci.     Publication Date:  1987 Nov 
Date Detail:
Created Date:  1988-03-29     Completed Date:  1988-03-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0013105     Medline TA:  Isr J Med Sci     Country:  ISRAEL    
Other Details:
Languages:  eng     Pagination:  1128-31     Citation Subset:  IM    
Department of Pediatrics, Central Emek Hospital, Afula, Israel.
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MeSH Terms
Cross-Sectional Studies
Escherichia coli Infections / complications*
Food Hypersensitivity / epidemiology*,  etiology
Gastroenteritis / complications*
Milk / adverse effects*
Milk Proteins / adverse effects*
Reg. No./Substance:
0/Milk Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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