| Prevalence of peripheral arterial disease: persistence of excess risk in former smokers. | |
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MedLine Citation:
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PMID: 12141616 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To determine the age-standardised prevalence of peripheral arterial disease (PAD) and associated risk factors, particularly smoking. METHOD: Design: Cross-sectional survey of a randomly selected population. Setting: Metropolitan area of Perth, Western Australia. Participants: Men aged between 65-83 years. RESULTS: The adjusted response traction was 77.2%. Of 4,470 men assessed, 744 were identified as having PAD by the Edinburgh Claudication Questionnaire and/ or the ankle-brachial index of systolic blood pressure, yielding an age-standardised prevalence of PAD of 15.6% (95% confidence intervals (CI): 14.5%: 16.6%). The main risk factors identified in univariate analyses were increasing age, smoking-current (OR = 3.9, 95% CI 2.9-5.1) or former (OR = 2.0, 95% CI 1.6-2.4), physical inactivity (OR = 1.4, 95% CI 1.2-1.7), a history of angina (OR = 2.2, 95% Cl 1.8-2.7) and diabetes mellitus (OR = 2.1, 95% Cl 1.7-2.6). The multivariate analysis showed that the highest relative risk associated with PAD was current smoking of 25 or more cigarettes daily (OR = 7.3, 95% Cl 4.2-12.8). In this population, 32% of PAD was attributable to current smoking and a further 40% was attributable to past smoking by men who did not smoke currently. CONCLUSIONS: This large observational study shows that PAD is relatively common in older, urban Australian men. In contrast with its relationship to coronary disease and stroke, previous smoking appears to have a long legacy of increased risk of PAD. IMPLICATIONS: This research emphasises the importance of smoking as a preventable cause of PAD. |
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Authors:
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Bess Fowler; Konrad Jamrozik; Paul Norman; Yvonne Allen |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Australian and New Zealand journal of public health Volume: 26 ISSN: 1326-0200 ISO Abbreviation: Aust N Z J Public Health Publication Date: 2002 |
Date Detail:
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Created Date: 2002-07-26 Completed Date: 2002-08-15 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9611095 Medline TA: Aust N Z J Public Health Country: Australia |
Other Details:
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Languages: eng Pagination: 219-24 Citation Subset: IM |
Affiliation:
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Department of Public Health, University of Western Australia, Crawley. bfowler@curtin.edu.au |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Arteries / pathology Body Mass Index Cross-Sectional Studies Humans Life Style Male Middle Aged Peripheral Vascular Diseases / epidemiology*, etiology Prevalence Questionnaires Risk Factors Smoking / adverse effects*, epidemiology Time Urban Health Western Australia / epidemiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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