Document Detail


Prevalence and outcome of congenital heart disease in patients with neural tube defect.
MedLine Citation:
PMID:  18056696     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A prospective clinical study was designed to establish the risk factors, the prevalence, and the progress of congenital heart defects in children with neural tube defects. Study included 90 children with a mean age of 13.5 +/- 30.4 months. There were 53 (59%) patients with spina bifida occulta and 37 (41%) patients with spina bifida aperta. The overall prevalence of congenital heart disease was 27.8% (40.5% in spina bifida aperta and 18.9% in spina bifida occulta; P = .024). There was no statistically significant difference for maternal age, usage of periconceptional folate, and maternal diabetes between the patient and control groups. The authors conclude that congenital heart defects are more common than reported in neural tube defects, and screening echocardiograms are warranted. This should be kept in mind especially in patients requiring minor or major surgical procedures. Furthermore, routine obstetric examination and therefore the use of periconceptional folic acid during pregnancy is still lacking in our country.
Authors:
Gülendam Koçak; Cagatay Onal; Ayhan Koçak; Cemsit Karakurt; Ozkan Ates; Süleyman R Cayli; Saim Yologlu
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2007-12-03
Journal Detail:
Title:  Journal of child neurology     Volume:  23     ISSN:  0883-0738     ISO Abbreviation:  J. Child Neurol.     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-05-01     Completed Date:  2008-07-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8606714     Medline TA:  J Child Neurol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  526-30     Citation Subset:  IM    
Affiliation:
Department of Pediatric Cardiology, Inonu University, Turgut Ozal Medical Center, Malatya, Turkey. gul_endam@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Child
Child, Preschool
Female
Heart Defects, Congenital / complications,  epidemiology*
Humans
Infant
Infant, Newborn
Male
Neural Tube Defects / complications,  epidemiology*
Prevalence
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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