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Prevalence of oral Candida carriage in Thai adolescents.
MedLine Citation:
PMID:  22298521     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Aim:  Oral candidiasis is among the most common AIDS-associated opportunistic infections. Adolescents remain at the highest risk of HIV infection and could suffer from oral candidiasis. However, information on oral Candida carriage in this population is limited. This study aims to evaluate the prevalence of oral Candida in Thai adolescents. Methods:  Oral rinse samples from 80 healthy Thais (age: 15-17 years) were collected and analyzed for the prevalence of Candida species using culture-based and polymerase chain reaction assays. Results:  Twenty six adolescents (32.5%) carried Candida in the oral cavity. Candida albicans was detected in 28.75% (23/80). Non-albicans Candida species were detected in 6.25% (5/80). The majority (92.3%, 24/26) of adolescents with Candida carried a single species. Two carried two species: one with Candida glabrata and Candida albicans, and the other with Candida parapsilosis and Candida albicans. Three adolescents harbored only non-albicans species, with one carrying Candida tropicalis and two carrying Candida parapsilosis. Candida dubliniensis was not detected in this population. Most adolescents carried Candida at a low level (<500 c.f.u./mL). Conclusions: Oral Candida was present in approximately one-third of adolescents. Candida albicans was the most prevalent (88.5%), and non-albicans species were present in 19.2% of those with oral Candida.
Authors:
Prapat Santiwongkarn; Supareok Kachonboon; Panida Thanyasrisung; Oranart Matangkasombut
Publication Detail:
Type:  Journal Article     Date:  2011-08-07
Journal Detail:
Title:  Journal of investigative and clinical dentistry     Volume:  3     ISSN:  2041-1626     ISO Abbreviation:  J Investig Clin Dent     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-02-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101524471     Medline TA:  J Investig Clin Dent     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  51-5     Citation Subset:  D; IM    
Copyright Information:
© 2011 Blackwell Publishing Asia Pty Ltd.
Affiliation:
Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand  Department of Microbiology and DRU on Oral Microbiology, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand  Laboratory of Biotechnology, Chulabhorn Research Institute, Bangkok, Thailand.
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