Document Detail

Prevalence of obesity in young adults with acute lymphoblastic leukemia.
MedLine Citation:
PMID:  7919428     Owner:  NLM     Status:  MEDLINE    
We studied the hormonal pattern of nine patients with acute lymphoblastic leukemia. The patients were treated with standard therapeutic regimens. They were overweight by a mean of 52% at the end of the consolidation treatment, and this persisted after a follow-up of 2 years. The only endocrine alteration observed was a moderate decrease in serum testosterone levels in male patients. The other parameters studied were in the normal range. We conclude that prolonged treatment with high doses of corticosteroids, which have a depressive effect on metabolism, was responsible for the obesity.
L Pagano; G De Rosa; M T Voso; R Marra; A Testa; G Leone
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of clinical & laboratory research     Volume:  24     ISSN:  0940-5437     ISO Abbreviation:  Int. J. Clin. Lab. Res.     Publication Date:  1994  
Date Detail:
Created Date:  1994-10-27     Completed Date:  1994-10-27     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9206491     Medline TA:  Int J Clin Lab Res     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  117-9     Citation Subset:  IM    
Istituto di Semeiotica Medica, Università Cattolica S. Cuore, Rome, Italy.
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MeSH Terms
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
Body Weight
Hormones / blood*
Obesity / blood,  etiology*
Precursor Cell Lymphoblastic Leukemia-Lymphoma / blood,  complications,  drug therapy*
Retrospective Studies
Testosterone / blood
Reg. No./Substance:
0/Hormones; 58-22-0/Testosterone

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