Document Detail

Prevalence of nosocomial infections in Swiss children's hospitals.
MedLine Citation:
PMID:  15484802     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To acquire data on pediatric nosocomial infections (NIs), which are associated with substantial morbidity and mortality and for which data are scarce. DESIGN: Prevalence survey and evaluation of a new comorbidity index. SETTING: Seven Swiss pediatric hospitals. PATIENTS: Those hospitalized for at least 24 hours in a medical, surgical, intensive care, or intermediate care ward. RESULTS: Thirty-five NIs were observed among 520 patients (6.7%; range per hospital, 1.4% to 11.8%). Bacteremia was most frequent (2.5 per 100 patients), followed by urinary tract infection (1.3 per 100 patients) and surgical-site infection (1.1 per 100 patients; 3.2 per 100 patients undergoing surgery). The median duration until the onset of infection was 19 days. Independent risk factors for NI were age between 1 and 12 months, a comorbidity score of 2 or greater, and a urinary catheter. Among surgical patients, an American Society of Anesthesiologists (ASA) score of 2 or greater was associated with any type of NI (P = .03). Enterobacteriaceae were the most frequent cause of NI, followed by coagulase-negative staphylococci; viruses were rarely the cause. CONCLUSIONS: This national prevalence survey yielded valuable information about the rate and risk factors of pediatric NI. A new comorbidity score showed promising performance. ASA score may be a predictor of NI. The season in which a prevalence survey is conducted must be considered, as this determines whether seasonal viral infections are observed. Periodic prevalence surveys are a simple and cost-effective method for assessing NI and comparing rates among pediatric hospitals.
Kathrin Mühlemann; Christine Franzini; Christoph Aebi; Christoph Berger; David Nadal; Jody Stähelin; Hanspeter Gnehm; Klara Posfay-Barbe; Alain Gervaix; Hugo Sax; Ulrich Heininger; Jan Bonhoeffer; Gerhard Eich; Christian Kind; Christiane Petignat; Pietro Scalfaro
Publication Detail:
Type:  Journal Article; Multicenter Study    
Journal Detail:
Title:  Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America     Volume:  25     ISSN:  0899-823X     ISO Abbreviation:  Infect Control Hosp Epidemiol     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2004-10-15     Completed Date:  2004-12-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8804099     Medline TA:  Infect Control Hosp Epidemiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  765-71     Citation Subset:  IM; N    
University Hospital, Bern, Switzerland.
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MeSH Terms
Age Distribution
Child, Preschool
Cross Infection / epidemiology*,  etiology,  prevention & control
Hospitals, Pediatric / statistics & numerical data*
Infant, Newborn
Logistic Models
Multivariate Analysis
Population Surveillance
Switzerland / epidemiology

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