Document Detail


Prevalence of non-calcified coronary plaque on 64-slice computed tomography in asymptomatic patients with zero and low coronary artery calcium.
MedLine Citation:
PMID:  20847965     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: To study the prevalence of noncalcified plaque in asymptomatic low-risk patients with no or mild coronary artery calcium (CAC).
METHODS: From 502 patients with coronary risk factors who underwent 64-slice computed tomography, 224 asymptomatic patients were identified with no CAC (n=117) or mild CAC (n=107; defined as patients with Agatston scores from 1 to 100).
RESULTS: Patients with no CAC were younger and had diabetes less often. Medications and laboratory data were not significantly different between the two groups. The prevalence of noncalcified plaque was 11.1% in patients with no CAC and 23.4% in the mild CAC group (P=0.0142). Multiple plaques were detected in 2.6% of the group with no CAC and 3.7% of the group with mild CAC (P=0.5934). Significant coronary artery stenosis was found in one patient in the group with no CAC (0.9%) and three patients in the group with mild CAC (2.8%, P=0.3506).
CONCLUSIONS: Significant percentages of noncalcified plaque were found in asymptomatic low-risk patients with no or mild coronary calcium.
Authors:
Kohichiro Iwasaki; Takeshi Matsumoto; Hitoshi Aono; Hiroshi Furukawa; Masanobu Samukawa
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Canadian journal of cardiology     Volume:  26     ISSN:  1916-7075     ISO Abbreviation:  Can J Cardiol     Publication Date:    2010 Aug-Sep
Date Detail:
Created Date:  2010-09-17     Completed Date:  2010-10-15     Revised Date:  2013-05-27    
Medline Journal Info:
Nlm Unique ID:  8510280     Medline TA:  Can J Cardiol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  377-80     Citation Subset:  IM    
Affiliation:
Department of Cardiology, Okayama Central Hospital, Okayama, Japan. kiwasaki@kyokuto.or.jp
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MeSH Terms
Descriptor/Qualifier:
Aged
Calcinosis / epidemiology,  metabolism*,  radiography*
Calcium / metabolism*
Coronary Artery Disease / epidemiology,  metabolism*,  radiography*
Coronary Vessels* / metabolism,  pathology
Female
Humans
Male
Middle Aged
Prevalence
Risk Factors
Severity of Illness Index
Tomography, X-Ray Computed*
Chemical
Reg. No./Substance:
7440-70-2/Calcium
Comments/Corrections
Comment In:
Can J Cardiol. 2010 Aug-Sep;26(7):381   [PMID:  20847966 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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