Document Detail

Prevalence of new-onset insomnia in patients with obstructive sleep apnoea syndrome treated with nocturnal ventilatory support.
MedLine Citation:
PMID:  22129574     Owner:  NLM     Status:  Publisher    
INTRODUCTION: New-onset insomnia (NOI) associated with nocturnal ventilatory support (NVS) is becoming a reality in clinical practice; however there is a lack of data about its prevalence. Our aim was to determine the prevalence of NOI in patients with obstructive sleep apnoea syndrome (OSAS) under NVS and its associated risk factors. MATERIAL AND METHODS: Descriptive cross-sectional study of 80 patients with OSAS under NVS. We compared two groups, with and without NOI, considering demographic characteristics, disease features, and personality. Patients under anxiolytic and/or antidepressant medication, with a weight loss of 10% or greater, and with restless legs symptoms were excluded. RESULTS: Median age of patients was 60.0 (interquartile range (IQR) 10.0) years; 82.5% were male. Median initial Epworth Sleepiness Scale (ESS) and apnoea-hypopnoea index (AHI) were 12.5 (IQR 9.0) and 44.1 (IQR 22.4)/hr, respectively. The majority of patients (91.3%) were under auto-adjusting positive airway pressure (APAP). Insomnia at baseline was present in 30% of patients (n=24). Prevalence of NOI was 21.4% (12/56). Initial and/or intermediate insomnia were the most frequent subtypes (n=11). We found a statistically significant negative relation between NOI and pressure on 90% night-time (P(90)) (p=0.040). CONCLUSIONS: OSAS patients under NVS presented a high prevalence of NOI. Patients with NOI presented lower levels of pressure using NVS, compared to the others.
P Caetano Mota; S Morais Cardoso; M Drummond; A C Santos; J Almeida; J C Winck
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-11-28
Journal Detail:
Title:  Revista portuguesa de pneumologia     Volume:  -     ISSN:  0873-2159     ISO Abbreviation:  -     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-12-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9813736     Medline TA:  Rev Port Pneumol     Country:  -    
Other Details:
Languages:  ENG; POR     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2010 Sociedade Portuguesa de Pneumologia. Published by Elsevier España. All rights reserved.
Serviço de Pneumologia, Hospital de São João, Porto, Portugal.
Vernacular Title:
Prevalência de insónia de novo em doentes com síndrome de apneia obstrutiva do sono tratados com suporte ventilatório nocturno.
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