Document Detail

Prevalence of neonatal ultrasound brain lesions in premature infants with and without intrauterine growth restriction.
MedLine Citation:
PMID:  17888056     Owner:  NLM     Status:  MEDLINE    
AIM: To compare the prevalence of transient periventricular echodensities (TPE), periventricular leukomalacia (PVL) and haemorrhagic brain lesions (HBL) in singleton intrauterine growth-restricted (IUGR) infants and in those appropriate for gestational age (AGA). METHODS: Thirty-five IUGR and 35 AGA singleton infants born between 24- and 34-week gestational age were studied. The presence of TPE, PVL and HBL was assessed with ultrasound (US) at day 3 (US-I), 2 weeks (US-II) after delivery and at term-equivalent age (US-III). RESULTS: IUGR neonates had an increased prevalence of TPE at US-I (18/35 vs. 8/35, p= 0.02) and an increased prevalence of PVL at US-II (8/32 vs. 1/31, p = 0.03) and US-III (8/29 vs. 1/29, p = 0.02). No significant differences in the prevalence of HBL were found between the two groups. CONCLUSIONS: IUGR is associated with an increased prevalence of white matter damage on US brain scans in preterm neonates.
Nelly F Padilla-Gomes; Goya Enríquez; Ruthy Acosta-Rojas; Josep Perapoch; Edgar Hernandez-Andrade; Eduard Gratacos
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-09-19
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  96     ISSN:  0803-5253     ISO Abbreviation:  Acta Paediatr.     Publication Date:  2007 Nov 
Date Detail:
Created Date:  2007-10-16     Completed Date:  2008-02-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  1582-7     Citation Subset:  IM    
Hospital Clínic-IDIBAPS, Obstetrics Department-ICGON, University of Barcelona, Spain.
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MeSH Terms
Cerebral Hemorrhage / epidemiology*,  ultrasonography
Cerebral Ventricles / pathology*,  ultrasonography
Fetal Growth Retardation / physiopathology*
Gestational Age
Infant, Newborn
Infant, Premature
Intensive Care Units, Neonatal / utilization
Leukomalacia, Periventricular / epidemiology*,  ultrasonography
Neurologic Examination
Prospective Studies
Spain / epidemiology

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