Document Detail

Prevalence of mitral valve prolapse in keratoconus patients.
MedLine Citation:
PMID:  1404188     Owner:  NLM     Status:  MEDLINE    
Fifty patients with advanced degrees of keratoconus, requiring corneal transplantation, were screened for mitral valve prolapse by two dimensional echocardiography. The overall prevalence of 58% was found to be statistically higher than the prevalence of 7% found in a group of age and sex-matched controls. It was also found to be higher than the previously reported prevalence of 38% in a group of keratoconus patients with similar age and sex match to our series. The findings of our study in conjunction with the histopathological and biochemical similarities between the two conditions strongly suggest that they may be different manifestations of similar defects in collagen metabolism.
K W Sharif; T A Casey; J Coltart
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the Royal Society of Medicine     Volume:  85     ISSN:  0141-0768     ISO Abbreviation:  J R Soc Med     Publication Date:  1992 Aug 
Date Detail:
Created Date:  1992-11-02     Completed Date:  1992-11-02     Revised Date:  2010-09-07    
Medline Journal Info:
Nlm Unique ID:  7802879     Medline TA:  J R Soc Med     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  446-8     Citation Subset:  IM    
Corneo-plastic Unit, Queen Victoria Hospital, East Grinstead, West Sussex.
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MeSH Terms
Keratoconus / complications*,  epidemiology
Middle Aged
Mitral Valve Prolapse / complications*,  epidemiology
Comment In:
J R Soc Med. 1992 Dec;85(12):773-4   [PMID:  1308132 ]
J R Soc Med. 1992 Dec;85(12):773   [PMID:  1494176 ]

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