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Prevalence of mitral valve prolapse and associated valvular regurgitations in healthy teenagers undergoing screening echocardiography.
MedLine Citation:
PMID:  20664768     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
BACKGROUND: The true prevalence of mitral valve prolapse (MVP) in the population has been controversial.
OBJECTIVE: To evaluate the prevalence of MVP and associated valvular abnormalities in healthy teenage students.
METHODS: The Anthony Bates Foundation performed screening echocardiography in high schools across the United States. A total of 2072 students between 13 and 19 years of age were identified for the present study.
RESULTS: Total prevalence of MVP was 0.7%. The prevalence of MVP was significantly higher among female teenagers (nine of 690 female teenagers [1.3%] versus five of 1382 male teenagers [0.4%], P=0.01, OR 3.6, CI 1.21 to 10.70). The prevalence of mitral regurgitation (MR) and tricuspid regurgitation (TR) was higher in teenagers with MVP. MR occurred in five of 14 teenagers (35.7%) with MVP versus 15 of 2058 controls (0.7%) (P<0.001, OR 75.6, CI 22.6 to 252.5). TR occurred in one of 14 teenagers (7.1%) with MVP versus nine of 2058 controls (0.4%) (P<0.001, OR 17.5, CI 2.0 to 148.3).
CONCLUSION: The prevalence of MVP in this cohort of healthy teenage students was less than 1%. Furthermore, the prevalence of MVP was higher in female teenagers and was associated with a higher prevalence of MR and TR.
Authors:
Sudhakar Sattur; Sharon Bates; Mohammad Reza Movahed
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Experimental and clinical cardiology     Volume:  15     ISSN:  1918-1515     ISO Abbreviation:  Exp Clin Cardiol     Publication Date:  2010  
Date Detail:
Created Date:  2010-07-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9715903     Medline TA:  Exp Clin Cardiol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  e13-5     Citation Subset:  -    
Affiliation:
Department of Medicine, Division of Cardiology, University of Arizona School of Medicine, Southern Arizona VA Health Care System and Sarver Heart Center, Tucson;
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