| Prevalence of metabolic syndrome in primary antiphospholipid syndrome patients. | |
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MedLine Citation:
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PMID: 20951239 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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OBJECTIVE: To estimate the prevalence of metabolic syndrome (MetS) in patients with primary antiphospholipid syndrome (PAPS). PATIENTS AND METHODS: Cross sectional study of PAPS patients from the outpatient clinic. MetS was based on three international definitions: World Health Organization (WHO), Adult Treatment Panel III (ATP III), or International Diabetes Federation (IDF). Clinical history and laboratory investigations, including insulin levels, lipid profile, glucose, and CRP, anthropometric and blood pressure measurements, were evaluated. Descriptive statistics was used. Kappa statistics examined the agreement between MetS definitions. RESULTS: 58 PAPS patients were studied, mean age 42.14±11.62, 9 men, 49 women. The most frequent cardiovascular risk (CVR) factors were hypertriglyceridemia, low HDL cholesterol levels, and visceral obesity. Prevalence of MetS was 17.2% according to WHO, 34.5% according to ATP III and 37.9% according to IDF criteria. MetS according to ATP III and WHO criteria was similar to the general population (34.5% vs. 36.8%) (17.2% vs. 13.6%), and lower according to IDF definition (37.9% vs. 49.8%). CONCLUSIONS: This study shows a high prevalence of MetS in PAPS patients, similar to that in the general population and other autoimmune diseases. Identification of MetS is very important to indicate preventive strategies and reduce cardiovascular morbidity and mortality in PAPS. |
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Authors:
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Gabriela Medina; Ana Laura Gutiérrez-Moreno; Olga Vera-Lastra; Miguel A Saavedra; Luis J Jara |
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Publication Detail:
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Type: Journal Article Date: 2010-10-14 |
Journal Detail:
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Title: Autoimmunity reviews Volume: 10 ISSN: 1873-0183 ISO Abbreviation: Autoimmun Rev Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-02-28 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101128967 Medline TA: Autoimmun Rev Country: Netherlands |
Other Details:
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Languages: eng Pagination: 214-7 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier B.V. All rights reserved. |
Affiliation:
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Clinical Research Unit, Hospital de Especialidades Centro Médico La Raza, IMSS, Mexico City, Mexico. |
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