Document Detail


Prevalence of lower genital tract infections among human immunodeficiency virus (HIV)-seropositive and high-risk HIV-seronegative women. HIV Epidemiology Research Study Group.
MedLine Citation:
PMID:  10524955     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study was undertaken to assess whether the prevalence of lower genital tract infections among human immunodeficiency virus (HIV)-seropositive women was higher than among high-risk HIV-seronegative women at their baseline visit for the HIV Epidemiology Research Study. Results were available for 851 HIV-seropositive and 434 HIV-seronegative women. Human papilloma virus (HPV) infection was more prevalent among HIV-seropositive women (64% vs. 28%). Bacterial vaginosis was common (35% vs. 33%), followed by trichomoniasis (12% vs. 10%), syphilis (8% vs. 6%), Chlamydia trachomatis infection (4% vs. 5%), candidal vaginitis (3% vs. 2%), and Neisseria gonorrhoeae infection (0.8% vs. 0.3%). Alcohol use (odds ratio [OR], 1.8; 95% confidence interval [CI], 1. 3-2.4) and smoking (OR, 1.8; 95% CI, 1.3-2.5) were associated with bacterial vaginosis. Bacterial vaginosis (OR, 2.3; 95% CI, 1.5-3.4), trichomoniasis (OR, 2.3; 95% CI, 1.1-4.7), and syphilis (OR, 3.1; 95% CI, 1.3-7.4) were found to be more prevalent among black women. Our study showed no statistically significant difference in the prevalence of lower genital tract infections except for HPV between HIV-infected and demographically and behaviorally similar HIV-uninfected high-risk women.
Authors:
S Cu-Uvin; J W Hogan; D Warren; R S Klein; J Peipert; P Schuman; S Holmberg; J Anderson; E Schoenbaum; D Vlahov; K H Mayer
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America     Volume:  29     ISSN:  1058-4838     ISO Abbreviation:  Clin. Infect. Dis.     Publication Date:  1999 Nov 
Date Detail:
Created Date:  1999-12-02     Completed Date:  1999-12-02     Revised Date:  2012-10-23    
Medline Journal Info:
Nlm Unique ID:  9203213     Medline TA:  Clin Infect Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1145-50     Citation Subset:  IM; X    
Affiliation:
Brown University, Providence, Rhode Island, USA. scu-uvin@RIHOSP.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
CD4 Lymphocyte Count
Female
Genital Diseases, Female / epidemiology*
HIV Seronegativity*
HIV Seropositivity / complications*
Humans
Papillomaviridae
Papillomavirus Infections / epidemiology
Prevalence
Syphilis / epidemiology
Trichomonas Infections / epidemiology
Vaginosis, Bacterial / epidemiology
Grant Support
ID/Acronym/Agency:
U64CU106795/CU/CSP VA; U64CU20678/CU/CSP VA; U64CU306802/CU/CSP VA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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