Document Detail

Prevalence of left ventricular diastolic dysfunction in newly diagnosed Nigerians with systemic hypertension: a pulsed wave Doppler echocardiographic study.
MedLine Citation:
PMID:  21326972     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Systemic hypertension is a common cause of left ventricular diastolic dysfunction. However, its prevalence in Nigerians with untreated systemic hypertension is unknown.
OBJECTIVE: To determine the prevalence of left ventricular diastolic dysfunction in newly diagnosed Nigerians with systemic hypertension using Doppler transmitral inflow and pulmonary venous flow velocities.
METHODS: Two-dimensional echocardiography including Doppler was performed on 150 newly diagnosed cases of systemic hypertension and 150 normotensive controls. They were divided into hypertensives without left ventricular hypertrophy and those with left ventricular hypertrophy based on echocardiographically determined left ventricular mass index. Pulsed Doppler transmitral inflow and the pulmonary venous flow waves were used to categorise the patterns of diastolic dysfunction.
RESULTS: The hypertensives and the normotensive controls were comparable in their baseline characteristics. The E/A ratio differed significantly between hypertensives with and without left ventricular hypertrophy and controls (1.00+0.30, 1.04±0.42, 1.33±0.27, p < 0.001). Left ventricular diastolic dysfunction occurred in 62% of systemic hypertension and 11.3% of the controls. Impaired relaxation was the commonest pattern (84.9%) of diastolic dysfunction.
CONCLUSION: Our study showed that left ventricular diastolic dysfunction is prevalent in Nigerians with newly diagnosed systemic hypertension and effort should be made to routinely screen for them.
G U Adamu; A I Katibi; George O Opadijo; A B O Omotoso; A M Araoye
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  African health sciences     Volume:  10     ISSN:  1729-0503     ISO Abbreviation:  Afr Health Sci     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2011-02-17     Completed Date:  2011-04-27     Revised Date:  2013-06-30    
Medline Journal Info:
Nlm Unique ID:  101149451     Medline TA:  Afr Health Sci     Country:  Uganda    
Other Details:
Languages:  eng     Pagination:  177-82     Citation Subset:  IM    
Department of Medicine, University of Ilorin, Teaching Hospital, PMB, Ilorin, Kwara state, Nigeria.
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MeSH Terms
African Continental Ancestry Group
Blood Pressure / physiology
Diastole / physiology*
Echocardiography, Doppler, Pulsed*
Heart Ventricles / ultrasonography
Hypertension / complications,  epidemiology,  physiopathology*,  ultrasonography*
Middle Aged
Nigeria / epidemiology
Ventricular Dysfunction, Left / complications,  epidemiology,  physiopathology*,  ultrasonography

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