Document Detail


Prevalence of interatrial block in patients with Friedreich's Ataxia.
MedLine Citation:
PMID:  20211503     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
METHODS: IAB, defined as an electrocardiographic (ECG) derived P-wave duration >120 ms, echocardiographic variables and genetic markers were evaluated in 23 FA patients with no manifestation of cardiac involvement and were compared to 23 sex- and age-matched controls.
RESULTS: IAB was significantly more frequent among FA patients compared to controls (11/23 vs 1/23, p<0.005 respectively). However, no correlations with echocardiographic parameters or Guanine-Adenine-Adenine (GAA) trinucleotide repeat lengths could be established.
CONCLUSION: Early recognition of IAB could allow the identification of asymptomatic FA patients who are prone to develop potentially life-threatening arrhythmias.
Authors:
Marios Panas; Elias Gialafos; Kostas Spengos; Theodore G Papaioannou; Konstantina Aggeli; Athina Kladi; Gerasimos Siasos; John Gialafos; Dimitrios Vassilopoulos; Christodoulos Stefanadis
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Publication Detail:
Type:  Letter     Date:  2010-03-07
Journal Detail:
Title:  International journal of cardiology     Volume:  145     ISSN:  1874-1754     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-12-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  386-7     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
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