| Prevalence of infection following hepatic chemoembolization with cross-linked collagen with administration of prophylactic antibiotics. | |
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MedLine Citation:
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PMID: 8186609 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: The authors present their experience with 494 hepatic chemoembolization (HCE) procedures in 236 patients with administration of a mixture of cross-linked collagen and chemotherapeutic agents. The prevalence of infectious complications was compared in patients who did and did not receive prophylactic administration of antibiotics as part of the HCE procedure. PATIENTS AND METHODS: Fourteen HCE procedures in nine patients were performed without prophylactic antibiotics (PA). These patients underwent embolization with cross-linked collagen alone or with low-dose cisplatinum. All of the remaining 480 procedures in 227 patients were performed with PA. RESULTS: One of the nine patients (11%) who did not receive PA experienced fatal sepsis within 24 hours of HCE. Of the 227 patients who did receive antibiotics, six (2.6%) developed hepatic abscess and no fatal sepsis was encountered. CONCLUSION: Use of PA decreases the prevalence of infectious complications following HCE. |
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Authors:
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R A Reed; G P Teitelbaum; J R Daniels; M J Pentecost; M D Katz |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Journal of vascular and interventional radiology : JVIR Volume: 5 ISSN: 1051-0443 ISO Abbreviation: J Vasc Interv Radiol Publication Date: 1994 Mar-Apr |
Date Detail:
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Created Date: 1994-06-23 Completed Date: 1994-06-23 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9203369 Medline TA: J Vasc Interv Radiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 367-71 Citation Subset: IM |
Affiliation:
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Department of Radiology, University of Southern California School of Medicine, Los Angeles. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Anti-Bacterial Agents / therapeutic use* Antineoplastic Agents / administration & dosage* Chemoembolization, Therapeutic / adverse effects* Collagen / administration & dosage* Female Humans Liver Abscess / epidemiology*, microbiology, prevention & control Liver Neoplasms / therapy Male Middle Aged Premedication Prevalence Retrospective Studies |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 0/Antineoplastic Agents; 121938-23-6/Angiostat; 9007-34-5/Collagen |
| Comments/Corrections | |
Comment In:
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J Vasc Interv Radiol. 1995 Jul-Aug;6(4):658-9
[PMID:
7579882
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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