| Prevalence, incidence and persistence of anti-asthma medication use in 2- to 29-year-olds: a nationwide prescription study. | |
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MedLine Citation:
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PMID: 19936728 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: The purpose of this study was to examine gender- and age-specific prevalence, incidence, and the type of anti-asthma medications used in the Norwegian population aged 2-29 years during 2005-2007 and to estimate the share of individuals who regularly redeemed medications over a 3-year period. METHODS: We retrieved data from the nationwide Norwegian Prescription Database for all individuals 2-29 years old (n = 1.7 million) who received anti-asthma medications during 2005-2007. Medications included inhaled short- and long-acting beta(2)-agonists, inhaled corticosteroids, fixed-dose combinations of inhaled beta(2)-agonists and corticosteroids, and leukotriene antagonists. RESULTS: In 2007, 5.5% (92,074 individuals) of Norwegians aged 2-29 years received anti-asthma medication, and this figure was stable throughout 2005-2007. Prevalence and incidence were higher among males than females but shifted to female dominance during adolescence. The share of anti-asthma medication users who received inhaled corticosteroids was high in preschool children but decreased by age. Conversely, use of inhaled beta(2)-agonists as monotherapy and of fixed combinations increased with age. Fewer than half the individuals were "persistent" to medication treatment for 3 years by redeeming prescriptions regularly (at least once a year). CONCLUSIONS: In this nationwide study, annual prevalence of anti-asthma medication use was stable during 2005-2007. The gender- and age-specific profile of prevalence and incidence correspond well with other studies. Fewer than half the individuals redeemed prescriptions regularly over 3 years. |
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Authors:
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Oystein Karlstad; Per Nafstad; Aage Tverdal; Svetlana Skurtveit; Kari Furu |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-11-21 |
Journal Detail:
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Title: European journal of clinical pharmacology Volume: 66 ISSN: 1432-1041 ISO Abbreviation: Eur. J. Clin. Pharmacol. Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-03-18 Completed Date: 2010-06-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 1256165 Medline TA: Eur J Clin Pharmacol Country: Germany |
Other Details:
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Languages: eng Pagination: 399-406 Citation Subset: IM |
Affiliation:
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Norwegian Institute of Public Health, Oslo, Norway. oystein.karlstad@fhi.no |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adrenal Cortex Hormones / therapeutic use* Asthma / drug therapy*, epidemiology* Child Databases, Factual Female Humans Incidence Leukotriene Antagonists / therapeutic use* Male Prescriptions* Prevalence |
| Chemical | |
Reg. No./Substance:
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0/Adrenal Cortex Hormones; 0/Leukotriene Antagonists |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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