| Prevalence, incidence, and mother-to-child transmission of HIV-1 in rural South Africa. | |
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MedLine Citation:
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PMID: 12241784 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Simple, robust approaches are needed to monitor prevalence, incidence, and mother-to-child transmission of HIV-1 in rural Africa. We have designed a method that uses antibody and viral RNA testing of dried blood spots obtained from mother-infant pairs attending routine immunisation clinics. In our study, prevalence and incidence of HIV-1 was highest in young women in their late teens and early twenties. In children born to infected mothers, prevalence increased from 14% in infants younger than 6 weeks of age to 24% at 3-6 months. The blood-spot approach is an effective method for surveillance of HIV-1 in women and children, and for early identification of incidence of this infection in women of child-bearing age. |
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Authors:
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N C Rollins; M Dedicoat; S Danaviah; T Page; K Bishop; I Kleinschmidt; H M Coovadia; S A Cassol; |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Lancet Volume: 360 ISSN: 0140-6736 ISO Abbreviation: Lancet Publication Date: 2002 Aug |
Date Detail:
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Created Date: 2002-09-20 Completed Date: 2002-10-01 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 2985213R Medline TA: Lancet Country: England |
Other Details:
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Languages: eng Pagination: 389 Citation Subset: AIM; IM |
Affiliation:
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Africa Centre for Health and Population Studies, KwaZulu, Natal, South Africa. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Female HIV Infections / diagnosis, epidemiology, transmission* HIV-1* Humans Incidence Infant Infant, Newborn Infectious Disease Transmission, Vertical* Pregnancy Prevalence Rural Health* South Africa / epidemiology |
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