Document Detail

Prevalence of hepatitis B virus markers among blood donors in a tertiary hospital in Tabuk, northwestern Saudi Arabia.
MedLine Citation:
PMID:  18400539     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: This study was carried out to determine the prevalence of hepatitis B virus (HBV) markers among blood donors in a tertiary hospital in Tabuk, northwestern Saudi Arabia. MATERIALS AND METHODS: A cross-sectional survey was done among male Saudi voluntary blood donors at the blood bank of the King Khalid tertiary care hospital in the northwest region of Saudi Arabia. A total of 3192 subjects were included in the study over the period from June 1, 2005 to May 31, 2006. Subjects were tested for evidence of HBV infection plus other relevant blood-borne pathogens. A questionnaire sheet for the collection of personal information (such as name, age, and sex), socioeconomic data (such as marital status, education, and occupation), family history of HBV infection, history of immunization against HBV, and history of past exposure to a high risk procedure or behavior, was prepared and used for each subject. Data were tabulated and statistically analyzed. RESULTS: Among the studied sample, the prevalence of HBsAg (hepatitis B surface antigen) was found to be 3.0% and the prevalence of anti-HBc (anti-hepatitis B core antigen) was found to be 18.7%. Blood donors with positive HBV markers showed significant association with increased age, being married, lower educational level, specific occupations such as blue collar worker and the military, family history of HBV infection, and lack of immunization. However, there was no significant association with history of exposure to high-risk procedure or behavior. CONCLUSIONS: The prevalence of HBV infection among male Saudi blood donors in the northwest region of Saudi Arabia is high compared to that reported from the central capital area (Riyadh). Public health education programs on HBV infection, adult hepatitis B immunization programs, and raising socioeconomic standards should be initiated in order to target the high-risk groups found in this study. Furthermore, a community-based study is recommended to investigate HBV infection in the northwest region of Saudi Arabia.
Kamel E El Beltagy; Ibrahem A Al Balawi; Maha Almuneef; Ziad A Memish
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Publication Detail:
Type:  Journal Article     Date:  2008-04-08
Journal Detail:
Title:  International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases     Volume:  12     ISSN:  1201-9712     ISO Abbreviation:  Int. J. Infect. Dis.     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-09-02     Completed Date:  2008-12-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610933     Medline TA:  Int J Infect Dis     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  495-9     Citation Subset:  IM    
Department of Infection Prevention and Control, King Abdulaziz Medical City, PO Box 22490, Riyadh 11426, Saudi Arabia.
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MeSH Terms
Age Distribution
Biological Markers / blood
Blood Donors / statistics & numerical data*
Cross-Sectional Studies
Hepatitis B Antibodies / blood*
Hepatitis B Core Antigens / immunology
Hepatitis B Surface Antigens / blood*
Hepatitis B, Chronic / epidemiology*
Middle Aged
Risk Factors
Saudi Arabia / epidemiology
Social Class
Young Adult
Reg. No./Substance:
0/Biological Markers; 0/Hepatitis B Antibodies; 0/Hepatitis B Core Antigens; 0/Hepatitis B Surface Antigens

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